Kim Young Soo, Kim Do Hyung, Yang Tae Won, Kim Minhwa, Lee Jeongrim, Cho Wonhyun, Kwon Oh Young
Department of Neurology, Gyeongsang National University Hospital, Jinju, Korea.
Department of Neurology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
J Clin Neurol. 2020 Oct;16(4):668-673. doi: 10.3988/jcn.2020.16.4.668.
The increased demand for donor organs has made it crucial to keep the organs of patients with impending brain death (PWIBDs) suitable for transplantation during the process of determining brain death. This study aimed to identify the time taken to determine brain death (TT-BD) in PWIBDs and the associated influencing factors.
This study analyzed data collected by the Korean Organ Donation Agency from 15 hospitals in the Yeongnam region of South Korea. There were 414 PWIBDs eligible for inclusion in this study. The data consisted of the TT-BD for PWIBDs and the potential variables influencing the TT-BD.
The mean age of the 414 PWIBDs was 48.9 years, and 120 of them were female (29.0%). The mean TT-BD was 8.5 days. The presence of spontaneous movements (SMs) and craniotomy significantly affected the TT-BD. The mean TT-BDs were 13.9 and 8.2 days in the PWIBDs with and without SMs, respectively, and 9.8 and 8.0 days in the PWIBDs with and without craniotomy, respectively.
The SMs in PWIBDs and a craniotomy performed immediately before starting the process of determining brain death seem to be related to lengthening the TT-BD.
对供体器官需求的增加使得在判定脑死亡过程中，保持即将脑死亡患者（PWIBDs）的器官适合移植变得至关重要。本研究旨在确定PWIBDs判定脑死亡所需时间（TT - BD）及其相关影响因素。
本研究分析了韩国器官捐献机构从韩国岭南地区15家医院收集的数据。有414例PWIBDs符合纳入本研究的条件。数据包括PWIBDs的TT - BD以及影响TT - BD的潜在变量。
414例PWIBDs的平均年龄为48.9岁，其中120例为女性（29.0%）。平均TT - BD为8.5天。自发运动（SMs）和开颅手术显著影响TT - BD。有和没有SMs的PWIBDs的平均TT - BD分别为13.9天和8.2天，有和没有开颅手术的PWIBDs的平均TT - BD分别为9.8天和8.0天。
PWIBDs中的SMs以及在开始判定脑死亡过程前立即进行的开颅手术似乎与延长TT - BD有关。
