INSERM UMR 1033, University of Lyon, Hôpital Edouard Herriot, Lyon, France.
Curr Osteoporos Rep. 2020 Dec;18(6):633-645. doi: 10.1007/s11914-020-00623-1. Epub 2020 Oct 8.
Low muscle strength and poor physical performance are associated with high risk of fracture. Many studies assessed clinical and functional outcomes of fractures. Fewer studies analyzed the impact of fractures on muscle strength and physical performance.
Vertebral fractures (especially multiple and severe ones) are associated with back pain, back-related disability, lower grip strength, lower strength of lower limbs, lower gait speed, and poor balance. Patients with hip fracture have slower gait and lower quadriceps strength. Non-vertebral fractures were associated with lower strength of the muscles adjacent to the fracture site (e.g., grip strength in the case of distal radius fracture, knee extensors in the case of patellar fracture) and poor physical function dependent on the muscles adjacent to the fracture site (e.g., limited range of motion of the shoulder in the case of humerus fracture, gait disturbances in the case of the ankle fracture). Individuals with a fracture experience a substantial deterioration of muscle strength and physical performance which exceeds that related to aging and is focused on the period close to the fracture occurrence. After fracture, muscle strength increased and physical performance improved. The rate of normalization depended partly on the therapeutic approach and on the rehabilitation program. A subgroup of patients, mainly the elderly, never returns to the pre-fracture level of physical performance. The permanent decline of physical function after fracture may be related to the limitation of movements due to pain, low physical activity, poor health before the fracture, and reduced efficacy of retraining after immobilization.
肌肉力量低和身体机能差与骨折风险增加相关。许多研究评估了骨折的临床和功能结局。较少的研究分析了骨折对肌肉力量和身体机能的影响。
椎体骨折(尤其是多发性和严重的椎体骨折)与背痛、腰背相关残疾、握力降低、下肢力量降低、步行速度降低和平衡不良相关。髋部骨折患者的步行速度较慢,股四头肌力量较弱。非椎体骨折与骨折部位附近肌肉力量降低(例如,桡骨远端骨折时的握力,髌骨骨折时的膝关节伸肌)和与骨折部位附近肌肉相关的身体机能降低(例如,肱骨干骨折时的肩关节活动范围受限,踝关节骨折时的步态障碍)有关。骨折患者的肌肉力量和身体机能会出现明显下降,其下降程度超过与年龄相关的下降程度,并且主要集中在骨折发生前后的时期。骨折后,肌肉力量增加,身体机能改善。正常化的速度部分取决于治疗方法和康复计划。一部分患者,主要是老年人,其身体机能永远无法恢复到骨折前的水平。骨折后身体机能的永久性下降可能与疼痛、体力活动减少、骨折前健康状况不佳以及固定后再训练效果降低导致的活动受限有关。