Van Dyk J
Radiother Oncol. 1987 Jun;9(2):107-18. doi: 10.1016/s0167-8140(87)80198-6.
Total body irradiation (TBI) is becoming increasingly prominent as a major component of therapy for patients with hematological diseases requiring bone marrow transplantation. This review considers some of the special dosimetric problems associated with TBI. Basic beam dosimetry and factors affecting dose variation within the patient are discussed and compared to conventional radiotherapy. The delivery of an accurate dose to the patient requires phantom measurements to be related to the dose at the prescription point. The use of treatment planning dose calculation procedures, including inhomogeneity corrections, is described specifically for large field treatments. Finally, some questions for future research are considered.
全身照射（TBI）作为血液系统疾病患者骨髓移植治疗的主要组成部分，正变得越来越重要。本综述探讨了与TBI相关的一些特殊剂量测定问题。讨论了基本射束剂量测定以及影响患者体内剂量变化的因素，并与传统放射治疗进行了比较。要向患者准确输送剂量，需要将模体测量结果与处方点处的剂量相关联。具体介绍了针对大野治疗的治疗计划剂量计算程序的使用，包括不均匀性校正。最后，考虑了一些未来研究的问题。
