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胰腺血管肉瘤——一例罕见腹痛病因的病例报告

Pancreas angiosarcoma-Case report of a rare cause of abdominal pain.

作者信息

Faria Aldara, Lopes Filipe, Figueira Alberto, Miranda Carlos, Coutinho João

机构信息

Departamento de Cirurgia Geral, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal; Faculdade de Medicina da Universidade de Lisboa, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal.

Departamento de Cirurgia Geral, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal.

出版信息

Int J Surg Case Rep. 2020;76:116-120. doi: 10.1016/j.ijscr.2020.09.131. Epub 2020 Sep 23.

DOI:10.1016/j.ijscr.2020.09.131
PMID:33032040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7551979/
Abstract

INTRODUCTION

Pancreas angiosarcoma is a very aggressive malignant neoplasm. The symptoms are nonspecific and it is usually diagnosed at an advanced stage, which confers a poor prognosis.

PRESENTATION OF CASE

We present a 56-year-old woman with abdominal epigastric pain and nausea. The abdominal CT-scan showed a 7 cm mass within the head of the pancreas and the pathology and immunochemistry analysis were positive for pancreas angiosarcoma. Intra-operatively the tumor was irresectable.

DISCUSSION

Pancreas angiosarcoma is an extremely rare neoplasm with non-specific diagnosis. The histology has a wide range of presentations and immunohistochemistry is required. The surgery appears to be the only effective treatment.

CONCLUSION

We report the seventh case of pancreas angiosarcoma in the English literature. Despite it's irresectability, the patient was asymptomatic two months after surgery, initiating chemotherapy with paclitaxel, with good tolerance.

摘要

引言

胰腺血管肉瘤是一种极具侵袭性的恶性肿瘤。其症状不具特异性,通常在晚期才被诊断出来,预后较差。

病例介绍

我们报告一名56岁女性,有上腹部疼痛和恶心症状。腹部CT扫描显示胰腺头部有一个7厘米的肿块,病理和免疫化学分析确诊为胰腺血管肉瘤。术中发现肿瘤无法切除。

讨论

胰腺血管肉瘤是一种极其罕见的肿瘤,诊断不具特异性。组织学表现多样,需要进行免疫组织化学检查。手术似乎是唯一有效的治疗方法。

结论

我们报告了英文文献中第七例胰腺血管肉瘤病例。尽管肿瘤无法切除,但患者术后两个月无症状,开始使用紫杉醇进行化疗,耐受性良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e757/7551979/cec00c59b14c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e757/7551979/2cdca11cad95/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e757/7551979/5110c8ac664a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e757/7551979/cec00c59b14c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e757/7551979/2cdca11cad95/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e757/7551979/5110c8ac664a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e757/7551979/cec00c59b14c/gr3.jpg

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