Department of Chemical Engineering, College of Engineering, Dhofar University, Salalah, Oman.
School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.
Curr Pharm Des. 2020;26(45):5793-5806. doi: 10.2174/1381612826666201008165241.
Biopolymers and their composites have been extensively investigated in recent years for multiple applications, especially in environmental, medical, and pharmaceutical fields. Bacterial cellulose (BC) has emerged as a novel biomaterial owing to its nontoxic, high-liquid absorbing and holding capacity, drug-carrying ability, and pollutant absorbing features. Additionally, its web-shaped three-dimensional (3D) structure and hydrogen bonding sites have incited a combination of various nanoparticles, polymers, and other materials with BC in the form of composites. Such BC-based composites have been developed through in-situ, ex-situ, and solution casting methods for targeted applications, such as air and water filters, controlled drug delivery systems, wound dressing materials, and tissue regeneration. This review details the production and development of BCbased composites with different materials and by various methods. It further describes various applications of BC-based composites in the environmental and pharmaceutical sectors, with specific examples from the recent literature. This review could potentially appeal a wide readership in these two emerging fields, where novel and advanced materials for different applications have been developed on a regular basis using BC as the base material.
近年来,生物聚合物及其复合材料因其在环境、医疗和制药等多个领域的广泛应用而受到广泛研究。细菌纤维素(BC)因其无毒、高吸液和保液能力、载药能力和污染物吸附特性而成为一种新型生物材料。此外,其网状三维(3D)结构和氢键结合位点激发了各种纳米粒子、聚合物和其他材料与 BC 形成复合材料的结合。已经通过原位、异位和溶液浇铸方法开发了基于 BC 的复合材料,用于空气和水过滤器、控制药物释放系统、伤口敷料材料和组织再生等靶向应用。本综述详细介绍了不同材料和不同方法制备的基于 BC 的复合材料的生产和发展。它进一步描述了基于 BC 的复合材料在环境和制药领域的各种应用,从最近的文献中列举了具体的例子。对于这两个新兴领域的广泛读者来说,这篇综述可能会很有吸引力,因为在这两个领域中,经常使用 BC 作为基础材料来开发用于不同应用的新型和先进材料。