Department of Veterinary Pathobiology, Veterinary Medical Diagnostic Laboratory, University of Missouri, 901 East Campus Loop, Columbia, MO 65211, USA.
Vet Clin North Am Food Anim Pract. 2020 Nov;36(3):509-524. doi: 10.1016/j.cvfa.2020.08.007.
This article addresses diagnostic challenges involving toxicology cases that are multifactorial in nature, often involving sublethal exposures to multiple toxicants and/or other etiologies that are not toxic. Gold standard diagnostic approaches were developed under the assumption that cases were undoubtedly intoxications, and they still are applicable to those cases. A more integrated diagnostic approach, focusing on the initial problem list, is consistent with how veterinarians diagnose most cases. Livestock ownership attitudes continue to evolve. Ongoing threats to the financial well-being of animal agriculture ultimately will have an impact on the ability of producers to maintain health and performance of livestock.
本文讨论了涉及多因素的毒理学病例的诊断挑战,这些病例通常涉及亚致死暴露于多种毒物和/或其他非毒性病因。金标准诊断方法是在假设病例无疑是中毒的情况下制定的,它们仍然适用于这些病例。更综合的诊断方法,侧重于初始问题清单,与兽医诊断大多数病例的方法一致。畜牧业所有者的态度在不断变化。对动物农业财务健康的持续威胁最终将影响生产者维持牲畜健康和性能的能力。