The gravitostat theory: More data needed.
作者信息
Ohlsson Claes, Jansson John-Olov
机构信息
Institute of Neuroscience and Physiology, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.
出版信息
EClinicalMedicine. 2020 Oct 3;27:100530. doi: 10.1016/j.eclinm.2020.100530. eCollection 2020 Oct.
Abstract
摘要
相似文献
1
The gravitostat theory: More data needed.重力稳定器理论：需要更多数据。
EClinicalMedicine. 2020 Oct 3;27:100530. doi: 10.1016/j.eclinm.2020.100530. eCollection 2020 Oct.
2
Studies in microgravity, simulated microgravity and gravity do not support a gravitostat.在微重力、模拟微重力和重力条件下的研究并不支持重力平衡假说。
J Endocrinol. 2020 Dec;247(3):273-282. doi: 10.1530/JOE-20-0393.
3
The Gravitostat Regulates Fat Mass in Obese Male Mice While Leptin Regulates Fat Mass in Lean Male Mice.Gravitostat 在肥胖雄性小鼠中调节脂肪量，而瘦素在 lean 雄性小鼠中调节脂肪量。
Endocrinology. 2018 Jul 1;159(7):2676-2682. doi: 10.1210/en.2018-00307.
4
The Gravitostat theory: Body fat is lost but is fat-free mass preserved?重力稳定理论：身体脂肪会减少，但无脂肪体重会保持吗？
EClinicalMedicine. 2020 Oct 3;27:100531. doi: 10.1016/j.eclinm.2020.100531. eCollection 2020 Oct.
5
Interactions Between the Gravitostat and the Fibroblast Growth Factor System for the Regulation of Body Weight.重力平衡与成纤维细胞生长因子系统在调节体重中的相互作用。
Endocrinology. 2019 May 1;160(5):1057-1064. doi: 10.1210/en.2018-01002.
6
The dual hypothesis of homeostatic body weight regulation, including gravity-dependent and leptin-dependent actions.稳态体重调节的双重假说，包括依赖重力和依赖瘦素的作用。
Philos Trans R Soc Lond B Biol Sci. 2023 Oct 23;378(1888):20220219. doi: 10.1098/rstb.2022.0219. Epub 2023 Sep 4.
7
The gravitostat protects diet-induced obese rats against fat accumulation and weight gain.重力调节器可保护饮食诱导的肥胖大鼠免于脂肪堆积和体重增加。
J Neuroendocrinol. 2021 Aug;33(8):e12997. doi: 10.1111/jne.12997. Epub 2021 Jul 9.
8
Reply to Lund: Where does the gravitostat fit in?对伦德的回复：重力调节器处于什么位置？
Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1335. doi: 10.1073/pnas.1800116115. Epub 2018 Jan 23.
9
Weighing the evidence for a body mass-regulating gravitostat.权衡体重调节重力感受器的证据。
Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1334. doi: 10.1073/pnas.1800033115. Epub 2018 Jan 23.
10
Increased weight loading reduces body weight and body fat in obese subjects - A proof of concept randomized clinical trial.增加负重可减轻肥胖受试者的体重和体脂——一项概念验证性随机临床试验。
EClinicalMedicine. 2020 Apr 30;22:100338. doi: 10.1016/j.eclinm.2020.100338. eCollection 2020 May.
引用本文的文献
1
Body weight regulation models in humans: insights for testing their validity.人体体重调节模型：检验其有效性的见解
Nat Rev Endocrinol. 2025 Jul 24. doi: 10.1038/s41574-025-01149-1.
2
Diet composition and energy intake in humans.人类的饮食构成和能量摄入。
Philos Trans R Soc Lond B Biol Sci. 2023 Oct 23;378(1888):20220449. doi: 10.1098/rstb.2022.0449. Epub 2023 Sep 4.
3
Energy homeostasis from Lavoisier to control theory.能量平衡：从拉瓦锡到控制理论。
Philos Trans R Soc Lond B Biol Sci. 2023 Sep 11;378(1885):20220201. doi: 10.1098/rstb.2022.0201. Epub 2023 Jul 24.
本文引用的文献
1
The Gravitostat theory: Body fat is lost but is fat-free mass preserved?重力稳定理论：身体脂肪会减少，但无脂肪体重会保持吗？
EClinicalMedicine. 2020 Oct 3;27:100531. doi: 10.1016/j.eclinm.2020.100531. eCollection 2020 Oct.
2
Increased weight loading reduces body weight and body fat in obese subjects - A proof of concept randomized clinical trial.增加负重可减轻肥胖受试者的体重和体脂——一项概念验证性随机临床试验。
EClinicalMedicine. 2020 Apr 30;22:100338. doi: 10.1016/j.eclinm.2020.100338. eCollection 2020 May.
3
The Gravitostat Regulates Fat Mass in Obese Male Mice While Leptin Regulates Fat Mass in Lean Male Mice.Gravitostat 在肥胖雄性小鼠中调节脂肪量，而瘦素在 lean 雄性小鼠中调节脂肪量。
Endocrinology. 2018 Jul 1;159(7):2676-2682. doi: 10.1210/en.2018-00307.
4
Body weight homeostat that regulates fat mass independently of leptin in rats and mice.调节大鼠和小鼠脂肪量而不依赖于瘦素的体重稳态。
Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):427-432. doi: 10.1073/pnas.1715687114. Epub 2017 Dec 26.
Zotero 插件