Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Mycopathologia. 2020 Dec;185(6):1057-1067. doi: 10.1007/s11046-020-00492-3. Epub 2020 Oct 9.
A retrospective, single-center analysis of 14 cases of Candida endocarditis (from 355 candidemia cases during the years 2012-2019) revealed a high in-hospital mortality (57.1%), a high proportion of healthcare-associated infections (13/14) and a high treatment preference for echinocandins. Transthoracic echocardiography and F-FDG PET/CT had a sensitivity of 54.5% and 57.1%, respectively. Patients were older than previously described and most patients with Candida endocarditis had persistent candidemia for ≥ 3 days despite antifungal therapy.
回顾性分析了 2012 年至 2019 年间 355 例念珠菌血症病例中的 14 例念珠菌心内膜炎病例，结果显示院内死亡率较高（57.1%），与医疗保健相关的感染比例较高（13/14），且对棘白菌素类药物的治疗偏好较高。经胸超声心动图和 F-FDG PET/CT 的敏感性分别为 54.5%和 57.1%。患者年龄大于既往描述，且大多数念珠菌心内膜炎患者尽管接受了抗真菌治疗，但念珠菌血症仍持续≥3 天。
