Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mycopathologia. 2023 Dec;188(6):893-905. doi: 10.1007/s11046-023-00745-x. Epub 2023 Jun 5.
Intravascular diseases due to Candida species, including endocarditis and cardiac device-associated infections, are rare yet devastating manifestations of invasive candidiasis affecting an already vulnerable population. Despite their significant associated morbidity and mortality, limited prospective data exist to inform the optimal diagnostic and therapeutic approaches to these entities. Herein, we review the existing literature pertaining to the epidemiology, diagnosis, and management of infectious endocarditis, rhythm management device infections, and circulatory support device infections caused by Candida species and suggest areas for future research.
血管内疾病由念珠菌属引起,包括心内膜炎和心脏器械相关感染,是侵袭性念珠菌病的罕见但严重的表现形式,影响已经脆弱的人群。尽管这些疾病具有显著的相关发病率和死亡率,但目前有限的前瞻性数据可用于告知这些疾病的最佳诊断和治疗方法。本文回顾了有关念珠菌属引起的感染性心内膜炎、心律管理装置感染和循环支持装置感染的流行病学、诊断和管理的现有文献,并提出了未来研究的领域。