Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada;, Email:
Comp Med. 2020 Dec 1;70(6):542-550. doi: 10.30802/AALAS-CM-20-000027. Epub 2020 Oct 9.
This paper presents a retrospective review of the postmortem findings in a colony of wild-caught ground squirrels used in medical research. The species included in this study were Richardson's ground squirrel , Columbian ground squirrel and golden-mantled ground squirrel . The pathologic findings in 160 ground squirrels from this colony demonstrated a wide variety of conditions, with chronic nephritis and hepatic adenomas being the most frequent overall. All animals with gross lesions of chronic interstitial nephritis had both glomerular and tubulointerstitial disease upon microscopic examination. As the first review of pathology in a research colony of ground squirrels. this study provides data for use in comparative studies about rodent diseases and important information for those who maintain such animals for research.
本文对用于医学研究的野生地松鼠群体的尸检结果进行了回顾性研究。本研究包括三种地松鼠：草原犬鼠、哥伦比亚旱獭和金冠松鼠。该群体中 160 只地松鼠的病理发现表现出广泛的病变，其中慢性肾炎和肝腺瘤最为常见。所有肉眼有慢性间质性肾炎病变的动物在显微镜下均有肾小球和肾小管间质疾病。作为对地松鼠研究群体病理学的首次回顾性研究，本研究为啮齿动物疾病的比较研究提供了数据，并为那些为研究而饲养这些动物的人提供了重要信息。
