Sultan Shaheen, Mushtaq Hina, Manan Abdul
Department of Medicine, Liaquat National Hospital, Karachi, Pakistan.
J Coll Physicians Surg Pak. 2020 Sep;30(9):987-988. doi: 10.29271/jcpsp.2020.09.987.
Kikuchi-Fujimoto disease, also called necrotising histiocytic lymphadenitis, is a rare disease of usually benign outcome. A case of a 21-year female is reported here. She presented with high grade fever and cervical lymphadenopathy. She was started on anti-tubercular treatment (ATT) with suspicion of tuberculous lymphadenitis as she had very strong history of tubercular (TB) contact. Kikuchi-Fujimoto disease was diagnosed after cervical lymph node biopsy, thus ATT was stopped. She was treated with oral steroids and complete recovery was made. Of significant note, two of patient's siblings were treated for pulmonary TB, because of which she had strong history of direct TB contact. Although a few cases of Kikuchi-Fujimoto disease have been reported in Pakistan, this is first case being reported in setting of very strong positive history of TB contact. Key Words: Lymphadenitis, Tuberculosis, Kikuchi-Fujimoto disease.
菊池-藤本病,也称为坏死性组织细胞性淋巴结炎,是一种通常预后良好的罕见疾病。本文报告了一例21岁女性病例。她表现为高热和颈部淋巴结病。由于她有非常强烈的结核接触史,怀疑为结核性淋巴结炎,开始接受抗结核治疗(ATT)。经颈部淋巴结活检确诊为菊池-藤本病,因此停止了抗结核治疗。她接受了口服类固醇治疗并完全康复。值得注意的是,患者的两个兄弟姐妹接受了肺结核治疗,因此她有很强的直接结核接触史。尽管巴基斯坦已经报道了几例菊池-藤本病,但这是在有非常强烈的结核接触阳性史的情况下首次报道的病例。关键词:淋巴结炎、结核病、菊池-藤本病。