Brailski Kh, Dimitrov B, Matov V, Damianov B
Vutr Boles. 1987;26(3):43-50.
Thirty-four patients with gastric ulcer were treated with the new Bulgarian preparation pharmaxolon-Pharmachim, for 20 days under clinical conditions. A favourable effect on the clinical symptoms by the pharmaxolon treatment was established but the differences with the control placebo group were statistically insignificant. A total of 47.1% from the gastric ulcers were healed after 20-day treatment and in 32.3% were reduced in size but here the difference from the control placebo group was insignificant. Pharmaxolon, with its therapeutic effect equals the related foreign (Biogastrone, Ultranyl, Caved-S) and Bulgarian preparations (Alcid-V), hence it is recommended for the practice. Elevated transitory arterial pressure was observed in 41% of pharmaxolon-treated patients, not necessitating the discontinuation of the treatment. That requires a periodic control of the arterial pressure of the patients, treated with that new Bulgarian preparation.
34例胃溃疡患者在临床条件下使用保加利亚新药法马克索隆（Pharmaxolon - Pharmachim）治疗20天。法马克索隆治疗对临床症状有积极作用，但与对照安慰剂组相比，差异无统计学意义。20天治疗后，共有47.1%的胃溃疡愈合，32.3%的溃疡面积缩小，但与对照安慰剂组的差异不显著。法马克索隆的治疗效果与国外同类药物（胃泌素、优拉美、卡维地洛 - S）及保加利亚制剂（阿尔西德 - V）相当，因此推荐用于临床。41%接受法马克索隆治疗的患者出现短暂性动脉血压升高，但无需停药。这就需要对使用这种保加利亚新药治疗的患者定期监测动脉血压。
