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[急性胰腺炎的手术指征、时机及方法]

[Surgical indications, timing and method in acute pancreatitis].

作者信息

Lorenz D, Sill U, Petermann J, Eldin M K

出版信息

Zentralbl Chir. 1987;112(8):491-9.

PMID:3303749
Abstract

Treatment for acute pancreatitis was received by 462 patients at the Surgical Hospital of Greifswald University, between 1976 and 1986. Surgical therapy was applied to 117 of 141 patients with necrotising pancreatitis. Lethality rates were 46 per cent in a group with partial necrosis and 86 per cent in another with total necrosis. The Ranson approach was used in operations on 63 of 90 patients with partial necrosis. Their lethality amounted to 23 per cent. 27 patients were given surgical treatment, in spite of unfavourable prognosis, only up to ten days from onset of acute pancreatitis. Lethality in this group was 78.5 per cent. Proper localisation of the necrotic focus is important to prognosis, just as good timing of surgical intervention. Lethality rates were 25 per cent for resection in the caudal region and 38 per cent for necrosectomy of the pars lienalis. Necrosis in the head region entailed a lethality rate of 90 per cent in response to necrosectomy and a rate of 64 per cent with additional lavage. The prognosis of pancrease necrosis is affected by timing and method of surgery. Timing should depend on the clinical pattern, laboratory parameters as well as on findings recorded by computed tomography and ultrasound. Aetiological aspects and location of the process must be considered for choice of surgical techniques. Necrectomy, lavage, and revision of bile ducts seem to be adequate surgical methods.

摘要

1976年至1986年间,格赖夫斯瓦尔德大学外科医院的462名患者接受了急性胰腺炎治疗。141例坏死性胰腺炎患者中有117例接受了手术治疗。部分坏死组的死亡率为46%,全坏死组为86%。90例部分坏死患者中有63例手术采用了兰森方法,其死亡率为23%。27例患者尽管预后不佳,但在急性胰腺炎发病后仅10天内就接受了手术治疗,该组死亡率为78.5%。坏死灶的准确定位对预后很重要,手术干预的时机选择同样重要。尾侧区域切除的死亡率为25%,脾门部坏死切除术的死亡率为38%。头部区域坏死患者坏死切除术后死亡率为90%,加用灌洗后死亡率为64%。胰腺坏死的预后受手术时机和方法的影响。时机选择应取决于临床症状、实验室参数以及计算机断层扫描和超声检查结果。选择手术技术时必须考虑病因学因素和病变部位。坏死切除术、灌洗术和胆管修复术似乎是合适的手术方法。

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