Ratiner Iu A, Klimova Z V, Ulisko I N
Zh Mikrobiol Epidemiol Immunobiol. 1987 May(5):16-20.
The use of factor sera permitting the differentiation of the variants, described in earlier. works, among the flagellar antigens of E. coli, formally denoted as H2, H4, H7, H10 and H34 in accordance with their official nomenclature, has made it possible to reveal that each of these variants is widely spread among E. coli and occurs in bacteria of different O-groups. Besides, this study has shown the possibility of subdividing a number of formal H: O types into 2 or more serovars on the basis of differences in the factor composition of their antigens. The results obtained in this study suggest that in the process of the evolution of E. coli H-antigen variants differing in their factor composition have been formed as independent varieties; therefore, these variants do not reflect the features characteristic of individual strains, but constitute one of the diagnostic signs of serological classification, i. e. the differentiation of the species into various serovars.
利用能区分早期研究中所描述的大肠杆菌鞭毛抗原变异体的因子血清，这些变异体根据其官方命名法正式表示为H2、H4、H7、H10和H34，这使得揭示这些变异体中的每一个在大肠杆菌中广泛传播并存在于不同O群的细菌中成为可能。此外，这项研究表明，基于其抗原因子组成的差异，有可能将一些正式的H:O型细分为2个或更多血清型。本研究获得的结果表明，在大肠杆菌进化过程中，因子组成不同的H抗原变异体已形成为独立的变种；因此，这些变异体并不反映个别菌株的特征，而是构成血清学分类的诊断标志之一，即把该物种区分为各种血清型。
