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自然大肠杆菌群体中鞭毛抗原H1的血清学多样性

Serological variety of flagellar antigen H1 in natural Escherichia coli population.

作者信息

Ratiner Y, Latto I, Ulisko I, Alekseeva M, Siitonen A

机构信息

Mechnikov Research Institute for Vaccines and Sera, Russian Academy of Medical Science, Moscow.

出版信息

FEMS Immunol Med Microbiol. 1995 Jan;10(2):125-31. doi: 10.1111/j.1574-695X.1995.tb00021.x.

DOI:10.1111/j.1574-695X.1995.tb00021.x
PMID:7719280
Abstract

Variation of the Escherichia coli flagellar antigen H1 was studied among 120 human isolates belonging to more than 25 O:K serovars. Factor-specific antisera were prepared and shown to be useful in the identification of serological subtypes of H1. The three subtypes found were defined as H1abc, H1acd and H1abe. The H1abc corresponded to the standard flagellar antigen H1 present in 84% of all strains. It was found in all O groups except O15, O17 and O83. Eight O15 and two O17 strains studied were of subtype H1abe, while the one O83 strain studied was H1acd. Both subtypes H1abc and H1acd were found among strains within O6:K5, O6:K13 or O-non-typeable:K5 serovars.

摘要

在属于25种以上O:K血清型的120株人类大肠杆菌分离株中研究了鞭毛抗原H1的变异情况。制备了因子特异性抗血清,并证明其有助于鉴定H1的血清学亚型。发现的三种亚型被定义为H1abc、H1acd和H1abe。H1abc对应于所有菌株中84%存在的标准鞭毛抗原H1。除O15、O17和O83外,在所有O群中均发现了该亚型。研究的8株O15和2株O17菌株为H1abe亚型,而研究的1株O83菌株为H1acd亚型。在O6:K5、O6:K13或O-不可分型:K5血清型的菌株中均发现了H1abc和H1acd亚型。

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1
Serological variety of flagellar antigen H1 in natural Escherichia coli population.自然大肠杆菌群体中鞭毛抗原H1的血清学多样性
FEMS Immunol Med Microbiol. 1995 Jan;10(2):125-31. doi: 10.1111/j.1574-695X.1995.tb00021.x.
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[Use of factor-H sera for the differentiation of the flagellar antigens of Escherichia coli serological variants].[利用H因子血清鉴别大肠杆菌血清变种的鞭毛抗原]
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K1, K5 and O antigens of Escherichia coli in relation to serum killing via the classical and alternative complement pathways.大肠杆菌的K1、K5和O抗原与通过经典和替代补体途径的血清杀菌作用的关系。
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引用本文的文献

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Front Microbiol. 2016 Feb 15;7:135. doi: 10.3389/fmicb.2016.00135. eCollection 2016.
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Serology and genetics of the flagellar antigen of Escherichia coli O157:H7a,7c.大肠杆菌O157:H7a,7c鞭毛抗原的血清学与遗传学
J Clin Microbiol. 2003 Mar;41(3):1033-40. doi: 10.1128/JCM.41.3.1033-1040.2003.