Abdullah Turdimuhammad, Qurban Rayyan O, Bolarinwa Sherifdeen O, Mirza Ahmed A, Pasovic Mirza, Memic Adnan
Center of Nanotechnology, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Front Bioeng Biotechnol. 2020 Sep 15;8:568186. doi: 10.3389/fbioe.2020.568186. eCollection 2020.
Three-dimensional (3D) printing has experienced a steady increase in popularity for direct manufacturing, where complex geometric items can be produced without the aid of templating tools, and manufacturing waste can be remarkably reduced. While customized medical devices and daily life items can be made by 3D printing of thermoplastics, microbial contamination has been a serious obstacle during their usage. A very clever approaches to overcome this challenge is to incorporate antimicrobial metal or metal oxide (M/MO) nanoparticles within the thermoplastics during or prior to 3D printing. Many M/MO nanoparticles can prevent contamination from a wide range of microorganism, including antibiotic-resistant bacteria via various antimicrobial mechanisms. Additionally, they can be easily printed with thermoplastic without losing their integrity and functionality. In this mini review, we summarize recent advancements and discuss future trends related to the development of 3D printed antimicrobial thermoplastic nanocomposites by addition of M/MO nanoparticles.
三维（3D）打印在直接制造领域的受欢迎程度稳步上升，借助3D打印可在无需模板工具的情况下生产复杂几何形状的物品，并能显著减少制造废料。虽然定制医疗设备和日常生活用品可通过热塑性塑料的3D打印制成，但微生物污染一直是其使用过程中的严重障碍。一种克服这一挑战的巧妙方法是在3D打印期间或之前将抗菌金属或金属氧化物（M/MO）纳米颗粒掺入热塑性塑料中。许多M/MO纳米颗粒可通过各种抗菌机制防止多种微生物污染，包括耐抗生素细菌。此外，它们可轻松与热塑性塑料一起打印，而不会丧失其完整性和功能。在本综述中，我们总结了近期的进展，并讨论了通过添加M/MO纳米颗粒开发3D打印抗菌热塑性纳米复合材料的未来趋势。
