印度孟买一家三级政府医院感染 SARS-CoV-2 的新生儿的临床特征。
Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India.
机构信息
Department of Neonatology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India.
Department of Neonatology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India. Correspondence to: Dr Swati Manerkar, Department of Neonatology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai 400 022, Maharashtra, India.
出版信息
Indian Pediatr. 2020 Dec 15;57(12):1143-1146. doi: 10.1007/s13312-020-2070-9. Epub 2020 Oct 12.
OBJECTIVE
To describe the clinical and laboratory profile of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected neonates.
METHODS
This is a review of hospital records, conducted in a tertiary care public hospital. Medical records of neonates born from 1 April, 2020 to 31 May, 2020 were reviewed. Women admitted in labor were screened for SARS-CoV-2 infection based on the guidelines issued by Indian Council for Medical Research. Neonates were tested for SARS-CoV-2 infection once mother tested positive, which was after day 2 of life. Demographic, clinical features, laboratory tests and chest radiographs of SARS-CoV-2 infected neonates were reviewed and neonates were telephonically followed up till the age of 2 months.
RESULTS
Out of 1229 mothers, 185 tested positive (15.05%); 12 neonates (6.48%) tested positive for SARS-CoV-2 infection. All neonates were exclusively breastfed. Symptoms, if any, were mild and self-limiting. Serum lactate dehydrogenase and liver enzymes were elevated. All neonates were healthy and thriving well on follow-up.
CONCLUSION
SARS-CoV-2 infected neonates are mostly asymptomatic and thrive well on exclusive breastfeeding.
目的
描述严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）感染新生儿的临床和实验室特征。
方法
这是对一家三级保健公立医院的病历进行的回顾性研究。对 2020 年 4 月 1 日至 2020 年 5 月 31 日出生的新生儿的病历进行了回顾。根据印度医学研究理事会发布的指南，对临产的妇女进行 SARS-CoV-2 感染筛查。一旦母亲检测呈阳性（即出生后第 2 天），即对新生儿进行 SARS-CoV-2 感染检测。对 SARS-CoV-2 感染新生儿的人口统计学、临床特征、实验室检查和胸部 X 线片进行了回顾，并对其进行了电话随访，直至 2 个月大。
结果
在 1229 名母亲中，有 185 名（15.05%）检测呈阳性；12 名（6.48%）新生儿 SARS-CoV-2 检测呈阳性。所有新生儿均纯母乳喂养。如果有任何症状，也是轻微且自限性的。血清乳酸脱氢酶和肝酶升高。所有新生儿在随访时均健康且生长良好。
结论
SARS-CoV-2 感染的新生儿大多无症状，纯母乳喂养可使其茁壮成长。
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