SARS-CoV-2 阳性新生儿的临床病程。
The clinical course of SARS-CoV-2 positive neonates.
机构信息
Division of Pediatrics Neonatology and NICU, Ospedale Buon Consiglio Fatebenefratelli, Naples, Italy.
Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
出版信息
J Perinatol. 2020 Oct;40(10):1462-1469. doi: 10.1038/s41372-020-0715-0. Epub 2020 Jul 6.
Abstract
The COVID-19 pneumonia was firstly reported in Wuhan, China, in December 2019. The disease had a rapid spread all over the word becoming an international public health emergency. Limited data were available on COVID-19 positive neonates. We reviewed relevant literature to understand the clinical course of disease and transmission routes in affected neonates. The aim of the study was evaluating the clinical course and prognosis of SARS-CoV-2 positive neonates. Based on current literature, the hypothesis of vertical transmission of SARS-CoV-2, though conceivable, remains unproven. A research conducted on PubMed database from December 2019 to April 27, 2020 revealed that were reported 25 neonates affected by SARS-CoV-2. Main symptoms were fever, cough, or shortness of breath but often these neonates did not show other symptoms during length stay in hospital. No deaths occurred.
摘要
2019 年 12 月，中国武汉首次报告了 COVID-19 肺炎。该疾病迅速在全球蔓延，成为国际公共卫生紧急事件。关于 COVID-19 阳性新生儿的数据有限。我们回顾了相关文献，以了解受影响新生儿的疾病临床过程和传播途径。本研究旨在评估 SARS-CoV-2 阳性新生儿的临床过程和预后。根据目前的文献，SARS-CoV-2 垂直传播的假设虽然可以想象，但尚未得到证实。一项针对 2019 年 12 月至 2020 年 4 月 27 日 PubMed 数据库的研究显示，报告了 25 例 SARS-CoV-2 感染的新生儿。主要症状是发热、咳嗽或呼吸急促，但这些新生儿在住院期间往往没有出现其他症状。没有死亡病例。
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2
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Am J Perinatol. 2020 Jun;37(8):869-872. doi: 10.1055/s-0040-1710541. Epub 2020 May 2.
3
Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection.孕妇感染 SARS-CoV-2 导致的中期流产。
JAMA. 2020 Jun 2;323(21):2198-2200. doi: 10.1001/jama.2020.7233.
4
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An Pediatr (Engl Ed). 2020 Jun;92(6):373-374. doi: 10.1016/j.anpede.2020.04.001. Epub 2020 Apr 27.
5
Vaginal delivery in SARS-CoV-2-infected pregnant women in Northern Italy: a retrospective analysis.意大利北部感染 SARS-CoV-2 的孕妇的阴道分娩：一项回顾性分析。
BJOG. 2020 Aug;127(9):1116-1121. doi: 10.1111/1471-0528.16278. Epub 2020 May 28.
6
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Obstet Gynecol. 2020 Jul;136(1):65-67. doi: 10.1097/AOG.0000000000003926.
7
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Int J Gynaecol Obstet. 2020 Jul;150(1):47-52. doi: 10.1002/ijgo.13182. Epub 2020 May 17.
8
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9
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10
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