环氧化酶抑制剂萘普生钠和甲芬那酸对月经过多的控制。
Control of menorrhagia by the cyclo-oxygenase inhibitors naproxen sodium and mefenamic acid.
作者信息
Hall P, Maclachlan N, Thorn N, Nudd M W, Taylor C G, Garrioch D B
出版信息
Br J Obstet Gynaecol. 1987 Jun;94(6):554-8. doi: 10.1111/j.1471-0528.1987.tb03150.x.
Abstract
Thirty-five patients with menorrhagia were treated in a double-blind crossover study with naproxen sodium and mefenamic acid after measurement of their blood loss during control menstrual cycles. Treatment with these compounds reduced the excessive bleeding by an average of 46 and 47% respectively. Drugs in the prostaglandin synthetase inhibitor group are considered to have an important place in the treatment of menorrhagia.
摘要
在一项双盲交叉研究中，对35名月经过多的患者在测量其对照月经周期的失血量后，使用萘普生钠和甲芬那酸进行治疗。使用这些化合物治疗分别使过多出血平均减少了46%和47%。前列腺素合成酶抑制剂组的药物被认为在月经过多的治疗中占有重要地位。
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