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咪唑对离子载体诱导的高眼压的影响。

Effect of imidazole on ionophore-induced ocular hypertension.

作者信息

Podos S M

出版信息

Invest Ophthalmol Vis Sci. 1977 Sep;16(9):853-5.

PMID:330451
Abstract

The effect of intraperitoneal injections of imidazole on the elevation of intraocular pressure produced by the topical application of the cation ionophores A23187 or X537A was studied in rabbits. Pretreatment with 200 mg./kg. imidazole completely inhibited the ocular hypertension induced by 1.0 percent A23187. The elevation of intraocular pressure produced by 0.5 percent X537A was not blocked by pretreatment with imidazole.

摘要

研究了腹腔注射咪唑对家兔局部应用阳离子离子载体A23187或X537A所引起的眼压升高的影响。用200毫克/千克咪唑预处理可完全抑制1.0% A23187引起的高眼压。0.5% X537A所引起的眼压升高未被咪唑预处理所阻断。

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