Advanced Specialty Program in Endodontics, University of California, San Francisco School of Dentistry, San Francisco, California.
Advanced Specialty Program in Endodontics, University of California, San Francisco School of Dentistry, San Francisco, California.
J Endod. 2021 Feb;47(2):247-252. doi: 10.1016/j.joen.2020.09.021. Epub 2020 Oct 10.
Regenerative endodontic procedures are undertaken on permanent teeth with necrotic pulps and open apices in an attempt to resolve symptoms, to allow the continued development of the root(s), and to reestablish vitality. The available histologic analysis of these teeth has, in the majority of studies, shown that true regeneration of the pulp-dentin complex is not achieved. A recent investigation using an animal model outlined a procedure wherein pulpal amputation a few millimeters short of the apex followed by evoked bleeding allowed the complete regeneration of the normal pulp-dentin complex in immature vital teeth of ferrets. By implementation of this procedure, we report successful pulp regeneration outcome evidenced by continued root development and a positive response to pulp vitality tests in a maxillary central incisor with an open apex diagnosed with symptomatic irreversible pulpitis.
再生性牙髓治疗是针对有坏死牙髓和根尖敞开的恒牙进行的，目的是缓解症状、促进牙根继续发育并恢复活力。大多数研究的组织学分析显示，牙髓-牙本质复合体的真正再生并未实现。最近一项使用动物模型的研究概述了一种方法，即在根尖几毫米处进行牙髓切断术，然后引发出血，可使雪貂未成熟的活髓恒切牙的正常牙髓-牙本质复合体完全再生。通过实施该程序，我们报告了一个成功的牙髓再生案例，该案例中，上颌中切牙的根尖敞开，诊断为症状性不可复性牙髓炎，其牙根继续发育，牙髓活力测试呈阳性反应。
