• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Transient expression of choline acetyltransferase-like immunoreactivity in Purkinje cells of the developing rat cerebellum.

作者信息

Gould E, Butcher L L

出版信息

Brain Res. 1987 Aug;431(2):303-6. doi: 10.1016/0165-3806(87)90218-5.

DOI:10.1016/0165-3806(87)90218-5
PMID:3304542
Abstract

The expression of choline acetyltransferase (ChAT)-like immunoreactivity was studied immunohistochemically in the cerebelli of developing rats. Brains were examined from the day of birth (postnatal day 1: P1) until adulthood. From P4 through P21, several Purkinje cells in the uvula, nodule, and flocculus of the cerebellum demonstrated ChAT-like immunoreactivity. After P23, no ChAT-positive neurons were observed in any region of the cerebellum. This finding paralleled the transient expression of acetylcholinesterase in Purkinje cells of these same cerebellar areas during development.

摘要

相似文献

1
Transient expression of choline acetyltransferase-like immunoreactivity in Purkinje cells of the developing rat cerebellum.
Brain Res. 1987 Aug;431(2):303-6. doi: 10.1016/0165-3806(87)90218-5.
2
The cholinergic system in developing cerebellum: comparative study of normal, hypothyroid and underfed rats.
Dev Neurosci. 1989;11(3):188-204. doi: 10.1159/000111898.
3
Secondary vestibular cholinergic projection to the cerebellum of rabbit and rat as revealed by choline acetyltransferase immunohistochemistry, retrograde and orthograde tracers.通过胆碱乙酰转移酶免疫组织化学、逆行和顺行示踪剂揭示的家兔和大鼠小脑的继发性前庭胆碱能投射。
J Comp Neurol. 1992 Mar 15;317(3):250-70. doi: 10.1002/cne.903170304.
4
Development of cholinesterase histochemical staining in cerebellar cortex: transient expression of "nonspecific" cholinesterase in Purkinje cells of the nodulus and uvula.小脑皮质胆碱酯酶组织化学染色的发育:蚓小结和小舌浦肯野细胞中“非特异性”胆碱酯酶的短暂表达。
Exp Neurol. 1991 Dec;114(3):330-42. doi: 10.1016/0014-4886(91)90159-a.
5
Zonation in the rat cerebellar cortex: patches of high acetylcholinesterase activity in the granular layer are congruent with Purkinje cell compartments.大鼠小脑皮质的分区:颗粒层中高乙酰胆碱酯酶活性斑块与浦肯野细胞区室一致。
Brain Res. 1988 May 17;448(2):237-51. doi: 10.1016/0006-8993(88)91261-9.
6
Cholinergic innervation of the cerebellum of rat, rabbit, cat, and monkey as revealed by choline acetyltransferase activity and immunohistochemistry.通过胆碱乙酰转移酶活性和免疫组织化学揭示大鼠、兔、猫和猴小脑的胆碱能神经支配。
J Comp Neurol. 1992 Mar 15;317(3):233-49. doi: 10.1002/cne.903170303.
7
Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons.啮齿动物皮层固有的胆碱乙酰转移酶免疫反应性神经元及其与乙酰胆碱酯酶阳性神经元的区别。
Neuroscience. 1984 Oct;13(2):341-53. doi: 10.1016/0306-4522(84)90234-3.
8
Asynchrony in the expression of guanosine 3':5'-phosphate-dependent protein kinase by clusters of Purkinje cells during the perinatal development of rat cerebellum.
Neuroscience. 1984 Dec;13(4):1217-41. doi: 10.1016/0306-4522(84)90295-1.
9
Evidence for an intracerebellar acetylcholinesterase-rich but probably non-cholinergic flocculo-nodular projection in the rat.大鼠小脑内富含乙酰胆碱酯酶但可能非胆碱能的绒球小结叶投射的证据。
Brain Res. 1983 Jan 3;258(1):115-9. doi: 10.1016/0006-8993(83)91234-9.
10
Regional distributions of choline acetyltransferase and acetylcholinesterase activities in layers of rat cerebellar vermis.大鼠小脑蚓部各层中胆碱乙酰转移酶和乙酰胆碱酯酶活性的区域分布。
J Histochem Cytochem. 1983 Jul;31(7):927-37. doi: 10.1177/31.7.6854006.

引用本文的文献

1
The dynamic effects of nicotine on the developing brain.尼古丁对发育中大脑的动态影响。
Pharmacol Ther. 2009 May;122(2):125-39. doi: 10.1016/j.pharmthera.2009.02.003. Epub 2009 Mar 5.
2
Selective vulnerability of cerebellar granule neuroblasts and their progeny to drugs with abuse liability.小脑颗粒神经母细胞及其后代对具有成瘾性药物的选择性易损性。
Cerebellum. 2003;2(3):184-95. doi: 10.1080/14734220310016132.
3
Effect of nicotine on cerebellar granule neuron development.尼古丁对小脑颗粒神经元发育的影响。
Eur J Neurosci. 2001 Jan;13(1):48-56.
4
The cholinergic innervation of the rat cerebral cortex shows two distinct phases in development.大鼠大脑皮层的胆碱能神经支配在发育过程中表现出两个不同阶段。
Exp Brain Res. 1989;76(2):417-23. doi: 10.1007/BF00247899.