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猪胃肠道研究前的饲养管理。

Feeding management before gastrointestinal studies in pigs.

机构信息

Wellcome Critical Care Laboratory for Large Animals, Dryden Farm, University of Edinburgh, UK.

Division of Imaging and Technology, School of Medicine, University of Dundee, UK.

出版信息

Lab Anim. 2021 Apr;55(2):177-180. doi: 10.1177/0023677220960509. Epub 2020 Oct 12.

Abstract

Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.

摘要

猪因其大小、生理和行为与人类相似,常被用于胃肠道(GI)研究模型:两者都是单胃杂食动物。一种用于测试新型 tethered ultrasound capsule endoscopes(USCE)的猪外科模型需要一个干净、运动活跃的小肠。在进行机械上相似的视频胶囊内镜检查过程之前,推荐对人类胃肠道进行准备,描述使用口服泻药,而在结直肠手术前推荐高碳水化合物饮料。有关于猪胃肠道准备的报道,但缺乏技术细节,即给药、疗效和副作用。本报告详细介绍了对 11 头接受手术和 USCE 的雌性猪进行高能量液体饮食喂养,这种饮食容易接受和管理,并且可以产生干净、运动活跃的小肠,没有发现可检测到的生理/行为异常。

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