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Brucellosis Presenting With Pancytopenia and Foot Drop.以全血细胞减少和足下垂为表现的布鲁氏菌病
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Pancytopenia As the Initial Manifestation of Brucellosis in Children.全血细胞减少作为儿童布鲁氏菌病的初始表现
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Kaleidoscopic presentation of neurobrucellosis.神经型布鲁氏菌病的万花筒样表现。
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[Neurological involvement in brucellosis; clinical classification, treatment and results].[布鲁氏菌病的神经系统受累;临床分类、治疗及结果]
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Ceftriaxone use in brucellosis: A case series.头孢曲松在布鲁氏菌病中的应用:病例系列
IDCases. 2019 Sep 5;18:e00633. doi: 10.1016/j.idcr.2019.e00633. eCollection 2019.
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A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis.骨关节炎布鲁氏菌病患病率的系统评价和荟萃分析。
PLoS Negl Trop Dis. 2019 Jan 18;13(1):e0007112. doi: 10.1371/journal.pntd.0007112. eCollection 2019 Jan.
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Clinical Manifestations in 82 Neurobrucellosis Patients from Kosovo.科索沃82例神经型布鲁氏菌病患者的临床表现
Mater Sociomed. 2016 Dec;28(6):408-411. doi: 10.5455/msm.2016.28.408-411.
4
A prospective study of brucellosis in children: relative frequency of pancytopenia.儿童布鲁氏菌病的前瞻性研究:全血细胞减少症的相对发生率
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Brucellosis in low-income and middle-income countries.布鲁氏菌病在中低收入国家的流行情况。
Curr Opin Infect Dis. 2013 Oct;26(5):404-12. doi: 10.1097/QCO.0b013e3283638104.
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Neurobrucellosis: clinical and diagnostic features.神经布鲁菌病:临床和诊断特征。
Clin Infect Dis. 2013 May;56(10):1407-12. doi: 10.1093/cid/cit072. Epub 2013 Feb 27.
7
Central nervous system brucellosis: presentation, diagnosis and treatment.中枢神经系统布鲁氏菌病:临床表现、诊断与治疗
J Infect. 1998 May;36(3):297-301. doi: 10.1016/s0163-4453(98)94279-7.
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Recognition and optimum treatment of brucellosis.布鲁氏菌病的识别与最佳治疗
Drugs. 1997 Feb;53(2):245-56. doi: 10.2165/00003495-199753020-00005.
9
Neurobrucellosis: clinical characteristics, diagnosis, and outcome.神经型布鲁氏菌病:临床特征、诊断及预后
Neurology. 1989 Apr;39(4):498-501. doi: 10.1212/wnl.39.4.498.

以全血细胞减少和足下垂为表现的布鲁氏菌病

Brucellosis Presenting With Pancytopenia and Foot Drop.

作者信息

Inayat Asad, Marwat Qudrat U, Hayat Waqar, Faisal Muhammad S

机构信息

Internal Medicine, Khyber Teaching Hospital, Peshawar, PAK.

Internal Medicine, Portiuncula University Hospital, Galway, IRL.

出版信息

Cureus. 2020 Sep 7;12(9):e10293. doi: 10.7759/cureus.10293.

DOI:10.7759/cureus.10293
PMID:33047083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7540186/
Abstract

Brucellosis is a zoonotic bacterial infection and is highly treatable. Despite being eradicated from most developed countries, its prevalence in Africa, the Middle East and parts of Asia pose a high risk of morbidity if undiagnosed. It mainly affects the reticuloendothelial system and manifests as fever, constitutional symptoms, hepatomegaly, and splenomegaly, but other organ systems can also be involved. Neurobrucellosis is a type of brucellosis in which the central or peripheral nervous systems are affected. It can present with a myriad of signs and symptoms such as stroke, meningitis, and cranial nerve palsies. We present a rare case of a 16-year-old boy with brucellosis who presented with pancytopenia and foot drop. He was subsequently managed with intravenous antibiotics for brucellosis and physiotherapy for foot drop.

摘要

布鲁氏菌病是一种人畜共患的细菌感染性疾病,且极易治疗。尽管在大多数发达国家已被根除,但在非洲、中东和亚洲部分地区,如果未被诊断出来,其流行会带来很高的发病风险。它主要影响网状内皮系统,表现为发热、全身症状、肝肿大和脾肿大,但其他器官系统也可能受累。神经型布鲁氏菌病是布鲁氏菌病的一种类型,其中枢或外周神经系统会受到影响。它可表现出多种体征和症状,如中风、脑膜炎和颅神经麻痹。我们报告一例罕见病例,一名16岁患布鲁氏菌病的男孩出现全血细胞减少和足下垂。随后他接受了针对布鲁氏菌病的静脉抗生素治疗以及针对足下垂的物理治疗。