Aziz-Ahari Alireza, Mamishi Setareh, Dadkhah Adeleh, Ghazinejadian-Sh Fatemeh S
Department of radiology, Iran university of medical sciences, Tehran, Iran.
Pediatric Infectious Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.
J Radiol Case Rep. 2019 Dec 31;13(12):13-19. doi: 10.3941/jrcr.v13i12.3734. eCollection 2019 Dec.
Brucellosis is a zoonotic multi-organ infectious disease most frequent in developing countries. Neurobrucellosis a quite rare but serious complication of brucellosis in the pediatric age group manifests with different neurological symptoms and signs. In the present case a 9-year-old girl was referred to our centre with a 9-months history of headache and back pain, facial nerve palsy and right upper limb weakness. She had undergone ventriculoperitoneal shunting surgery due to communicating hydrocephalus. Magnetic resonance imaging revealed a spinal extramedullary intradural mass, two epidural collections in the cervical spine and thickening/abnormal enhancement in the basal cisterns with invasion to medulla and pons. The patient's serum and cerebrospinal serologic tests were found positive for brucellosis. The patient was successfully treated by anti-brucella antibiotic therapy.
布鲁氏菌病是一种人畜共患的多器官传染病,在发展中国家最为常见。神经型布鲁氏菌病是布鲁氏菌病在儿童年龄组中一种相当罕见但严重的并发症,表现为不同的神经症状和体征。在本病例中,一名9岁女孩因头痛、背痛、面神经麻痹和右上肢无力9个月病史被转诊至我们中心。她因交通性脑积水接受了脑室腹腔分流手术。磁共振成像显示脊髓硬膜外髓外肿块、颈椎两处硬膜外积液以及基底池增厚/异常强化并侵犯延髓和脑桥。患者的血清和脑脊液血清学检测发现布鲁氏菌病呈阳性。患者通过抗布鲁氏菌抗生素治疗成功治愈。