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一名9岁女孩的神经型布鲁氏菌病

Neurobrucellosis in a 9-year-old girl.

作者信息

Aziz-Ahari Alireza, Mamishi Setareh, Dadkhah Adeleh, Ghazinejadian-Sh Fatemeh S

机构信息

Department of radiology, Iran university of medical sciences, Tehran, Iran.

Pediatric Infectious Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Radiol Case Rep. 2019 Dec 31;13(12):13-19. doi: 10.3941/jrcr.v13i12.3734. eCollection 2019 Dec.

DOI:10.3941/jrcr.v13i12.3734
PMID:32184924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7060014/
Abstract

Brucellosis is a zoonotic multi-organ infectious disease most frequent in developing countries. Neurobrucellosis a quite rare but serious complication of brucellosis in the pediatric age group manifests with different neurological symptoms and signs. In the present case a 9-year-old girl was referred to our centre with a 9-months history of headache and back pain, facial nerve palsy and right upper limb weakness. She had undergone ventriculoperitoneal shunting surgery due to communicating hydrocephalus. Magnetic resonance imaging revealed a spinal extramedullary intradural mass, two epidural collections in the cervical spine and thickening/abnormal enhancement in the basal cisterns with invasion to medulla and pons. The patient's serum and cerebrospinal serologic tests were found positive for brucellosis. The patient was successfully treated by anti-brucella antibiotic therapy.

摘要

布鲁氏菌病是一种人畜共患的多器官传染病,在发展中国家最为常见。神经型布鲁氏菌病是布鲁氏菌病在儿童年龄组中一种相当罕见但严重的并发症,表现为不同的神经症状和体征。在本病例中,一名9岁女孩因头痛、背痛、面神经麻痹和右上肢无力9个月病史被转诊至我们中心。她因交通性脑积水接受了脑室腹腔分流手术。磁共振成像显示脊髓硬膜外髓外肿块、颈椎两处硬膜外积液以及基底池增厚/异常强化并侵犯延髓和脑桥。患者的血清和脑脊液血清学检测发现布鲁氏菌病呈阳性。患者通过抗布鲁氏菌抗生素治疗成功治愈。

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Ann Med Surg (Lond). 2023 Apr 3;85(5):1385-1389. doi: 10.1097/MS9.0000000000000242. eCollection 2023 May.
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Diffuse Neurobrucellosis of Cerebellum, Brainstem, Spinal Cord, and Cauda Equina: A case report and Literature review.小脑、脑干、脊髓和马尾神经弥漫性神经型布鲁氏菌病:病例报告及文献复习。
J Radiol Case Rep. 2022 May 1;16(5):1-9. doi: 10.3941/jrcr.v16i5.3960. eCollection 2022 May.
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Neurobrucellosis: the great mimicker.神经型布氏杆菌病:模仿者中的大师。
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本文引用的文献

1
A Rare presentation of neurobrucellosis in a child with Recurrent transient ischemic attacks and pseudotumor cerebri (A case report and review of literature).一名患有复发性短暂性脑缺血发作和假性脑瘤的儿童的神经型布鲁氏菌病罕见表现(病例报告及文献综述)
Iran J Child Neurol. 2014 Spring;8(2):65-9.
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Neurobrucellosis: clinical and diagnostic features.神经布鲁菌病:临床和诊断特征。
Clin Infect Dis. 2013 May;56(10):1407-12. doi: 10.1093/cid/cit072. Epub 2013 Feb 27.
3
Pediatric neurobrucellosis associated with hydrocephalus.小儿神经型布鲁氏菌病合并脑积水
J Pediatr Neurosci. 2010 Jul;5(2):144-6. doi: 10.4103/1817-1745.76115.
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A case of neurobrucellosis presenting with isolated intracranial hypertension.一例以孤立性颅内高压为表现的神经型布鲁氏菌病。
J Child Neurol. 2011 Oct;26(10):1316-8. doi: 10.1177/0883073811402205. Epub 2011 May 6.
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Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature.1028 例布鲁氏菌病的临床表现和并发症:回顾性评估及文献复习。
Int J Infect Dis. 2010 Jun;14(6):e469-78. doi: 10.1016/j.ijid.2009.06.031. Epub 2009 Nov 11.
6
Overview of neurobrucellosis: a pooled analysis of 187 cases.神经型布鲁菌病概述:187 例汇总分析。
Int J Infect Dis. 2009 Nov;13(6):e339-43. doi: 10.1016/j.ijid.2009.02.015. Epub 2009 May 9.
7
Risk factors for human brucellosis in Iran: a case-control study.伊朗人间布鲁氏菌病的危险因素:一项病例对照研究。
Int J Infect Dis. 2008 Mar;12(2):157-61. doi: 10.1016/j.ijid.2007.04.019. Epub 2007 Aug 14.
8
Isolated intracranial hypertension: a rare presentation of neurobrucellosis.孤立性颅内高压:神经型布鲁氏菌病的一种罕见表现。
Microbes Infect. 2004 Jul;6(9):861-3. doi: 10.1016/j.micinf.2004.04.012.
9
Neurobrucellosis: clinical and neuroimaging correlation.神经型布鲁氏菌病:临床与神经影像学相关性
AJNR Am J Neuroradiol. 2004 Mar;25(3):395-401.
10
Diabetes insipidus in neurobrucellosis.神经型布鲁氏菌病中的尿崩症
Clin Neurol Neurosurg. 2000 Sep;102(3):163-5. doi: 10.1016/s0303-8467(00)00089-5.