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SMILE 术后小孔飞秒激光透镜切除术相关的视力恢复与术前球镜等效。

Visual recovery after small incision lenticule extraction (SMILE) in relation to pre-operative spherical equivalent.

机构信息

Singapore Eye Research Institute, The Academia, 20 College Road, Singapore, 169856, Singapore.

School of Primary, Community and Social Care, Keele University, Keele, Staffordshire, ST5 5BG, UK.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2021 Apr;259(4):1053-1060. doi: 10.1007/s00417-020-04954-8. Epub 2020 Oct 13.

Abstract

PURPOSE

To assess visual recovery after small incision lenticule extraction (SMILE) in relation to pre-operative spherical equivalent.

METHODS

Two hundred fourteen eyes of 107 patients were enrolled. Following surgery, patients were examined pre-operatively, 1 day, 2 weeks, 1 month and 3 months later. High myopia was defined as pre-operative spherical equivalent ≤ - 5 D. A linear mixed-effects model was used.

RESULTS

Mean ± standard deviation pre-operative spherical equivalent was - 5.30 ± 1.36 D that reduced significantly to 0.04 ± 0.70 D (p < 0.001) at 1 month and - 0.02 ± 0.66 D (p < 0.001) at 3 months. Mean pre-operative LogMAR uncorrected distance visual acuity ± SD was 0.97 ± 0.09 that improved significantly to 0.04 ± 0.06 at 2 weeks (p < 0.001), 0.01 ± 0.04 at 1 month (p < 0.001) and 0.01 ± 0.04 at 3 months (p < 0.001). Eighty-eight eyes (41.2%) had uncorrected distance visual acuities of 0.0 at 1 day, 154 eyes (72.0%) at 2 weeks,194 eyes (90.7%) at 1 month and 199 eyes (93.0%) at 3 months. Significantly more eyes with low myopia (> - 5 D) achieved acuities of 0.0 at 1 day and 2 weeks (p = 0.041 and p < 0.001). Post-operative acuities were not associated with refractive targets, laser cut energy settings or other variables. Two hundred nine eyes (97.7%) were within ± 0.5 D of target and 213 eyes (99.5%) were within ± 1 D.

CONCLUSIONS

SMILE for low myopia had faster visual recovery in the early post-operative period with no significant differences between groups detected by 1 and 3 months.

摘要

目的

评估小切口透镜切除术(SMILE)术后与术前等效球镜相关的视力恢复情况。

方法

纳入 107 例患者的 214 只眼。术后分别于术前、术后 1 天、2 周、1 个月和 3 个月进行检查。高度近视定义为术前等效球镜值≤-5D。采用线性混合效应模型进行分析。

结果

平均(±标准差)术前等效球镜值为-5.30±1.36D,术后 1 个月显著降低至 0.04±0.70D(p<0.001),术后 3 个月降低至-0.02±0.66D(p<0.001)。平均术前对数视力矫正(LogMAR)未矫正远视力值±标准差为 0.97±0.09,术后 2 周时显著提高至 0.04±0.06(p<0.001),术后 1 个月时提高至 0.01±0.04(p<0.001),术后 3 个月时提高至 0.01±0.04(p<0.001)。术后 1 天有 88 只眼(41.2%)未矫正远视力为 0.0,术后 2 周时 154 只眼(72.0%),术后 1 个月时 194 只眼(90.7%),术后 3 个月时 199 只眼(93.0%)。术后 1 天和 2 周时,更多低近视(>−5D)眼获得 0.0 的视力(p=0.041 和 p<0.001)。术后视力与屈光目标、激光切割能量设置或其他变量无关。209 只眼(97.7%)在目标值的±0.5D 范围内,213 只眼(99.5%)在目标值的±1D 范围内。

结论

SMILE 治疗低度近视的术后早期视力恢复更快,术后 1 个月和 3 个月时,各组之间无显著差异。

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