侵袭性 Merkel 细胞癌 1 例报告

Salah Azaiez Institute, University of Tunis El Manar, Tunis, Tunisia.

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620963714. doi: 10.1177/2324709620963714.

Merkel cell carcinoma (MCC) is a rare malignant neuroendocrine tumor more common in immunosuppressed old patients. It is characterized by a high frequency of local recurrence, regional nodal metastasis, distant metastasis, and low survival rate. The diagnosis of MCC is challenging due to its rarity and can be clinically mistaken for other skin cancer. We report a case of locally advanced MCC of the left groin with aggressive behavior that was finally controlled with a combined treatment and we collected data from the literature to discuss the appropriate therapeutic algorithm for the management of this uncommon skin tumor.

默克尔细胞癌（Merkel cell carcinoma，MCC）是一种罕见的恶性神经内分泌肿瘤，多见于免疫抑制的老年患者。其特点是局部复发、区域淋巴结转移、远处转移率高，生存率低。由于其罕见性，MCC 的诊断具有挑战性，临床上可能被误诊为其他皮肤癌。我们报告了一例左侧腹股沟局部晚期 MCC，表现为侵袭性行为，最终通过联合治疗得到控制。我们从文献中收集数据，讨论了管理这种罕见皮肤肿瘤的合适治疗方案。