Braman S S, Corrao W M
Clin Chest Med. 1987 Jun;8(2):177-88.
Cough is a complex physiologic event that protects the lungs from mechanical, chemical, and thermal injury. It is a normal reflex and therefore helps humans to adapt to an ever-changing environment. Cough can also be a pathologic reflex in that it may be an important and often the only sign of serious disease, may significantly contribute to the spread of airborne infection, and in some instances, may result in severe functional or structural damage to the organism. This article focuses on the pathophysiology of the afferent limb of the cough reflex, including a discussion of the causes, the diagnostic workup, and the treatment of cough.
咳嗽是一种复杂的生理活动,可保护肺部免受机械性、化学性和热性损伤。它是一种正常反射,有助于人类适应不断变化的环境。咳嗽也可能是一种病理反射,因为它可能是严重疾病的重要且往往是唯一的症状,可能会显著促进空气传播感染的扩散,并且在某些情况下,可能会对机体造成严重的功能或结构损伤。本文重点关注咳嗽反射传入支的病理生理学,包括对咳嗽的病因、诊断检查及治疗的讨论。