Ernst Glenda, Sabán Melina, Schiavone Miguel, Blanco Magalí, Salvado Alejandro, Borsini Eduardo
Centro de Medicina Respiratoria, Hospital Británico, Buenos Aires, Argentina. E-mail:
Comité Asesor Científico, Departamento de Docencia e Investigación, Hospital Británico, Buenos Aires, Argentina.
Medicina (B Aires). 2020;80(5):479-486.
Obstructive sleep apnea (OSA) is a prevalent condition. OSA is defined as very severe when the apneas/ hypopneas index (AHI) is greater than 60 events/hour. However, its prevalence remains uncertain. The aim of this study was to describe the prevalence and characteristics from patients with OSA according to severity. We performed a retrospective analysis of patients > 18 years, assessed by respiratory polygraph. We evaluated a total of 5670 patients with a mean of age of 54.4 ± 14.3 years old, of which 3606 were included in the OSA group. The overall prevalence of very severe OSA was 4.8%, being higher in men than in women (6.8 vs 1.9%). This group of patients was younger than the less severe groups (54.7 ± 13.9: mild OSA; 56.5 ± 12.9: moderate OSA; 57.9 ± 13.0: severe OSA vs 51.5 ± 12.9 years in the very severe patients; p < 0.0001). The results showed a significant increase in the body mass index (BMI) of patients with very severe OSA (31.6 ± 6.9: mild OSA, 32.8 ± 6.6: moderate OSA, 34.0 ± 6.8 severe OSA vs 37.1 ± 8.5 extreme severity; p < 0.0001), with similar results in men, but not in women. Finally, drowsiness due to ESS > 10, showed a significant increase in the very severe group of both sexes; 43.2% vs 31.5% (severe OSA); 26.4% (moderate OSA) and 23.8% (mild OSA). Very severe OSA presented a prevalence of 4.8% of patients with OSA. According to previous publications in other studied populations, we found that patients with very severe OSA are younger and more obese than the less severe groups.
阻塞性睡眠呼吸暂停(OSA)是一种常见病症。当呼吸暂停/低通气指数(AHI)大于60次/小时时,OSA被定义为非常严重。然而,其患病率仍不确定。本研究的目的是根据严重程度描述OSA患者的患病率和特征。我们对18岁以上通过呼吸多导仪评估的患者进行了回顾性分析。我们共评估了5670例患者,平均年龄为54.4±14.3岁,其中3606例纳入OSA组。非常严重OSA的总体患病率为4.8%,男性高于女性(6.8%对1.9%)。这组患者比病情较轻的组更年轻(54.7±13.9:轻度OSA;56.5±12.9:中度OSA;57.9±13.0:重度OSA,而非常严重患者为51.5±12.9岁;p<0.0001)。结果显示,非常严重OSA患者的体重指数(BMI)显著增加(31.6±6.9:轻度OSA,32.8±6.6:中度OSA,34.0±6.8:重度OSA,而极度严重为37.1±8.5;p<0.0001),男性结果相似,但女性并非如此。最后,ESS>10导致的嗜睡在非常严重组的两性中均显著增加;43.2%对31.5%(重度OSA);26.4%(中度OSA)和23.8%(轻度OSA)。非常严重OSA在OSA患者中的患病率为4.8%。根据之前在其他研究人群中的发表内容,我们发现非常严重OSA患者比病情较轻的组更年轻且更肥胖。