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[根据严重程度划分的阻塞性睡眠呼吸暂停的患病率及特征]

[Prevalence and characteristics of obstructive sleep apneas according to severity].

作者信息

Ernst Glenda, Sabán Melina, Schiavone Miguel, Blanco Magalí, Salvado Alejandro, Borsini Eduardo

机构信息

Centro de Medicina Respiratoria, Hospital Británico, Buenos Aires, Argentina. E-mail:

Comité Asesor Científico, Departamento de Docencia e Investigación, Hospital Británico, Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 2020;80(5):479-486.

Abstract

Obstructive sleep apnea (OSA) is a prevalent condition. OSA is defined as very severe when the apneas/ hypopneas index (AHI) is greater than 60 events/hour. However, its prevalence remains uncertain. The aim of this study was to describe the prevalence and characteristics from patients with OSA according to severity. We performed a retrospective analysis of patients > 18 years, assessed by respiratory polygraph. We evaluated a total of 5670 patients with a mean of age of 54.4 ± 14.3 years old, of which 3606 were included in the OSA group. The overall prevalence of very severe OSA was 4.8%, being higher in men than in women (6.8 vs 1.9%). This group of patients was younger than the less severe groups (54.7 ± 13.9: mild OSA; 56.5 ± 12.9: moderate OSA; 57.9 ± 13.0: severe OSA vs 51.5 ± 12.9 years in the very severe patients; p < 0.0001). The results showed a significant increase in the body mass index (BMI) of patients with very severe OSA (31.6 ± 6.9: mild OSA, 32.8 ± 6.6: moderate OSA, 34.0 ± 6.8 severe OSA vs 37.1 ± 8.5 extreme severity; p < 0.0001), with similar results in men, but not in women. Finally, drowsiness due to ESS > 10, showed a significant increase in the very severe group of both sexes; 43.2% vs 31.5% (severe OSA); 26.4% (moderate OSA) and 23.8% (mild OSA). Very severe OSA presented a prevalence of 4.8% of patients with OSA. According to previous publications in other studied populations, we found that patients with very severe OSA are younger and more obese than the less severe groups.

摘要

阻塞性睡眠呼吸暂停(OSA)是一种常见病症。当呼吸暂停/低通气指数(AHI)大于60次/小时时,OSA被定义为非常严重。然而,其患病率仍不确定。本研究的目的是根据严重程度描述OSA患者的患病率和特征。我们对18岁以上通过呼吸多导仪评估的患者进行了回顾性分析。我们共评估了5670例患者,平均年龄为54.4±14.3岁,其中3606例纳入OSA组。非常严重OSA的总体患病率为4.8%,男性高于女性(6.8%对1.9%)。这组患者比病情较轻的组更年轻(54.7±13.9:轻度OSA;56.5±12.9:中度OSA;57.9±13.0:重度OSA,而非常严重患者为51.5±12.9岁;p<0.0001)。结果显示,非常严重OSA患者的体重指数(BMI)显著增加(31.6±6.9:轻度OSA,32.8±6.6:中度OSA,34.0±6.8:重度OSA,而极度严重为37.1±8.5;p<0.0001),男性结果相似,但女性并非如此。最后,ESS>10导致的嗜睡在非常严重组的两性中均显著增加;43.2%对31.5%(重度OSA);26.4%(中度OSA)和23.8%(轻度OSA)。非常严重OSA在OSA患者中的患病率为4.8%。根据之前在其他研究人群中的发表内容,我们发现非常严重OSA患者比病情较轻的组更年轻且更肥胖。

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