Department of Epidemiology.
Department of Global Health.
AIDS. 2021 Jan 1;35(1):125-130. doi: 10.1097/QAD.0000000000002720.
Financial incentives can motivate desirable health behaviors, including adult HIV testing. Data regarding the effectiveness of financial incentives for HIV testing in children, who require urgent testing to prevent mortality, are lacking.
In a five-arm unblinded randomized controlled trial, adults living with HIV attending 19 HIV clinics in Western Kenya, with children 0-12 years of unknown HIV status, were randomized with equal allocation to $0, $1.25, $2.50, $5 or $10. Payment was conditional on child HIV testing within 2 months. Block randomization with fixed block sizes was used; participants and study staff were unblinded at randomization. Primary analysis was intent-to-treat, with predefined primary outcomes of completing child HIV testing and time to testing.
Of 452 caregivers, 90, 89, 93, 92 and 88 were randomized to $0, $1.25, $2.50, $5.00, and $10.00, respectively. Of those, 31 (34%), 31 (35%), 44 (47%), 51 (55%), and 54 (61%) in the $0, $1.25, $2.50, $5.00, and $10.00 arms, respectively, completed child testing. Compared with the $0 arm, and adjusted for site, caregivers in the $10.00 arm had significantly higher uptake of testing [relative risk: 1.80 (95% CI 1.15--2.80), P = 0.010]. Compared with the $0 arm, and adjusted for site, time to testing was significantly faster in the $5.00 and $10.00 arms [hazard ratio: 1.95 (95% CI 1.24--3.07) P = 0.004, 2.42 (95% CI 1.55--3.79), P < 0.001, respectively).
Financial incentives are effective in improving pediatric HIV testing among caregivers living with HIV.
NCT03049917.
经济激励可以激励人们养成理想的健康行为,包括成年人进行艾滋病毒检测。但是,对于需要紧急检测以预防死亡的儿童,缺乏关于经济激励对艾滋病毒检测效果的数据。
在一项五臂非盲随机对照试验中,肯尼亚西部 19 个艾滋病毒诊所的艾滋病毒感染者成年人与 0-12 岁儿童的艾滋病毒状况未知的儿童的照顾者参加了研究。他们按照相等的比例被随机分配到 0 美元、1.25 美元、2.50 美元、5 美元或 10 美元。支付条件是在 2 个月内完成儿童艾滋病毒检测。采用固定大小的块随机化;参与者和研究人员在随机化时被随机设盲。主要分析采用意向治疗,主要结局是完成儿童艾滋病毒检测和检测时间。
在 452 名照顾者中,分别有 90、89、93、92 和 88 名被随机分配到 0 美元、1.25 美元、2.50 美元、5.00 美元和 10.00 美元组。在这些组中,31(34%)、31(35%)、44(47%)、51(55%)和 54(61%)名照顾者的儿童完成了检测。与 0 美元组相比,并且根据地点进行调整后,10.00 美元组的照顾者的检测率显著更高[相对风险:1.80(95%置信区间 1.15-2.80),P=0.010]。与 0 美元组相比,并且根据地点进行调整后,5.00 美元和 10.00 美元组的检测时间明显更快[风险比:1.95(95%置信区间 1.24-3.07),P=0.004,2.42(95%置信区间 1.55-3.79),P<0.001]。
经济激励措施可有效提高艾滋病毒感染者照顾者对儿童艾滋病毒检测的参与度。
NCT03049917。