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急性脑血管疾病患者血液流变学参数与颅外颈动脉疾病的相关性

Hemorheologic parameters in correlation to extracranial carotid artery disease in patients with acute cerebrovascular disorders.

作者信息

Lechner H, Niederkorn K, Suzuki H

出版信息

Eur Neurol. 1987;27(3):139-41. doi: 10.1159/000116146.

DOI:10.1159/000116146
PMID:3305034
Abstract

In order to determine possible correlations to the extent of extracranial carotid artery disease (ECAD), the hemorheologic parameters (hematocrit, fibrinogen, whole blood and plasma viscosity, induced platelet aggregation) of 120 patients with acute cerebrovascular disorders (CVD) were studied and their carotid arteries were investigated by means of Duplex scanning. Plasma viscosity was only significantly elevated in CVD patients with severe ECAD (stenosis greater than 80% lumen reduction and/or occlusion) in comparison to CVD patients with normal to minimally diseased carotids and 67 normal controls. These results suggest that high plasma viscosity is an indicator for the existence of severe ECAD in CVD patients during the acute stage.

摘要

为了确定与颅外颈动脉疾病(ECAD)程度的可能相关性,对120例急性脑血管疾病(CVD)患者的血液流变学参数(血细胞比容、纤维蛋白原、全血和血浆粘度、诱导血小板聚集)进行了研究,并通过双功扫描对其颈动脉进行了检查。与颈动脉正常至轻度病变的CVD患者和67名正常对照相比,血浆粘度仅在患有严重ECAD(管腔狭窄大于80%和/或闭塞)的CVD患者中显著升高。这些结果表明,高血浆粘度是CVD患者急性期存在严重ECAD的一个指标。

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Eur Neurol. 1987;27(3):139-41. doi: 10.1159/000116146.
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