Brooks Arrin, Morris Mariah, Cuda Jonathan, Rahimpour Armein, Munie Semeret
Joan C Edwards School of Medicine, Marshall University, Huntington, WV, USA.
Department of Surgery, West Virginia University School of Medicine, Morgantown, WV, USA.
Case Rep Dermatol. 2023 Oct 25;15(1):202-216. doi: 10.1159/000531052. eCollection 2023 Jan-Dec.
Poroid hidradenoma (PH) is a rare benign adnexal tumor of eccrine differentiation. It is the rarest of the four described variants of poroid neoplasms. PHs characteristically share a hybrid of the architectural features of the hidradenoma, namely, tumor cells are entirely intradermal with both solid and cystic components, and the cytologic characteristics of the poroid neoplasms, containing predominantly poroid and cuticular cells. Many published reports of PH since its original discovery in 1990 state that "very few" cases of PH can be found in the literature. Here, we have identified a total of 75 published accounts of PH, including the case presented here, as well as the associated patient demographics, lesion characteristics, treatment, and outcomes. We suggest that while uncommon, PH is likely not exceptionally rare and could be an underreported diagnosis.
汗腺孔瘤(PH)是一种罕见的具有小汗腺分化的良性附属器肿瘤。它是所描述的四种汗腺孔瘤变体中最罕见的一种。汗腺孔瘤的特征是兼具汗腺腺瘤的结构特征,即肿瘤细胞完全位于真皮内,有实性和囊性成分,以及汗腺孔瘤的细胞学特征,主要包含汗腺孔和角质形成细胞。自1990年首次发现汗腺孔瘤以来,许多已发表的报告称文献中“极少”有汗腺孔瘤病例。在此,我们共识别出75篇已发表的关于汗腺孔瘤的报道,包括本文所呈现的病例,以及相关的患者人口统计学信息、病变特征、治疗方法和结果。我们认为,虽然汗腺孔瘤不常见,但可能并非极其罕见,可能是一种报告不足的诊断。