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80岁以上患者未破裂颅内动脉瘤的血管内弹簧圈栓塞术

Endovascular coil embolization for unruptured intracranial aneurysms in patients over 80 years of age.

作者信息

Lee Seok-Won, Kwon Hyon-Jo, Jeong Eun-Oh, Koh Hyeon-Song, Kim Kyung Hwan, Choi Seung-Won, Kim Seon-Hwan, Youm Jin-Young

机构信息

Department of Neurosurgery, Chungnam National University Hospital, Daejeon, Korea.

Department of Neurosurgery, School of Medicine, Chungnam National University, Daejeon, Korea.

出版信息

J Cerebrovasc Endovasc Neurosurg. 2020 Dec;22(4):237-244. doi: 10.7461/jcen.2020.E2020.08.002. Epub 2020 Oct 14.

Abstract

OBJECTIVE

As the average life span in modern society continues to increase, much interest is focused on high-risk procedures in elderly patients, including major surgical operations. We investigated the results of endovascular coiling of unruptured intracranial aneurysms (UIA) in patients over 80 years of age.

METHODS

We retrospectively analyzed 39 patients aged over 80 years who underwent coil embolization for UIA between April 2007 and April 2019 at our hospital.

RESULTS

Complete occlusion on digital subtraction angiography (DSA) immediately after surgery was performed in 44 (84.6%) of 52 cases of cerebral aneurysms. Four patients (7.7%) had residual aneurysmal necks, and four (7.7%) had contrast flow in the aneurysmal sac. Follow-up magnetic resonance angiography (mean: 8.2 months) was performed in 37 aneurysms in 24 patients. There was evidence of blood flow in the neck in seven cases (18.9%) and aneurysm in two cases (5.4%). Follow-up DSA (mean: 20.5 months) was performed in 14 aneurysms in 11 patients, and 11 aneurysms (78.6%) had complete occlusion, 1 aneurysm (7.1%) had an aneurysmal neck, and 2 aneurysms (14.3%) had contrast filling into the aneurysmal sac. Coil embolization procedure-related complications occurred in 3 patients (7.7%). Cerebral infarction occurred in 1 (2.6%), arterial dissection in 1 (2.6%), and hypoesthesia in 1 (2.6%).

CONCLUSIONS

Active treatment of UIA in elderly patients over 80 years of age through endovascular coil embolization can be considered.

摘要

目的

随着现代社会平均寿命持续增长,人们对老年患者的高风险手术操作,包括大型外科手术,给予了极大关注。我们调查了80岁以上患者未破裂颅内动脉瘤(UIA)的血管内栓塞治疗结果。

方法

我们回顾性分析了2007年4月至2019年4月在我院接受UIA线圈栓塞治疗的39例80岁以上患者。

结果

52例脑动脉瘤患者中,术后即刻数字减影血管造影(DSA)显示完全闭塞的有44例(84.6%)。4例(7.7%)有残留动脉瘤颈,4例(7.7%)动脉瘤囊内有造影剂充盈。对24例患者的37个动脉瘤进行了随访磁共振血管造影(平均:8.2个月)。7例(18.9%)有瘤颈血流证据,2例(5.4%)有动脉瘤复发。对11例患者的14个动脉瘤进行了随访DSA(平均:20.5个月),11个动脉瘤(78.6%)完全闭塞,1个动脉瘤(7.1%)有动脉瘤颈,2个动脉瘤(14.3%)动脉瘤囊内有造影剂充盈。3例(7.7%)发生了与线圈栓塞手术相关的并发症。1例(2.6%)发生脑梗死,1例(2.6%)发生动脉夹层,1例(2.6%)发生感觉减退。

结论

对于80岁以上老年患者的UIA,可考虑通过血管内线圈栓塞进行积极治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ee2/7820267/ae3f549ec75d/jcen-2020-e2020-08-002f1.jpg

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