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一名疑似肿瘤患者的葡萄胎:病例报告

Hydatidiform Mole in a Patient With a Concern for Neoplasia: A Case Report.

作者信息

Prabhu Indraneel K, Rosenbaum Amy

机构信息

Obstetrics and Gynecology, Touro University Nevada College of Medicine, Las Vegas, USA.

Obstetrics and Gynecology, Women's Health Associates of Southern Nevada, Las Vegas, USA.

出版信息

Cureus. 2020 Sep 8;12(9):e10319. doi: 10.7759/cureus.10319.

DOI:10.7759/cureus.10319
PMID:33052280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7544604/
Abstract

Molar pregnancy or a hydatidiform mole, also referred to as gestational trophoblastic disease, is an abnormal type of pregnancy, in which a potentially anomalous egg is abnormally fertilized resulting in a subsequently non-viable conceptus becoming an enlarged growth in the uterus with dangerous complications. These moles can occur as either complete or partial moles, each with its own unique features. In this article, we report a case of a pregnant woman who presented to her primary care doctor with the chief complaint of shortness of breath. Upon further questioning, she was found to have slight vaginal bleeding. Further workup of the unexplained bleeding revealed a small, yet concerning molar pregnancy, and led to our encounter with the patient on her operating day for a dilation and curettage. As these moles are somewhat rare occurrences, this case report aims to describe the condition, with a focus on management and outcomes.

摘要

葡萄胎,也称为妊娠滋养细胞疾病,是一种异常妊娠类型,其中一个潜在异常的卵子被异常受精,导致随后无法存活的胚胎在子宫内异常生长,并伴有危险的并发症。这些葡萄胎可分为完全性葡萄胎或部分性葡萄胎,每种都有其独特特征。在本文中,我们报告了一例孕妇,她因呼吸急促为主诉就诊于她的初级保健医生。进一步询问后,发现她有轻微阴道出血。对不明原因出血的进一步检查发现了一个虽小但令人担忧的葡萄胎,并导致我们在患者手术当天为其进行刮宫术时接触到该患者。由于这些葡萄胎较为罕见,本病例报告旨在描述这种情况,重点关注管理和结果。

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引用本文的文献

1
Gestational Trophoblastic Disease: Complete versus Partial Hydatidiform Moles.妊娠滋养细胞疾病:完全性与部分性葡萄胎
Diseases. 2024 Jul 17;12(7):159. doi: 10.3390/diseases12070159.
2
Diagnostic Utility of TSSC3 and RB1 Immunohistochemistry in Hydatidiform Mole.TSSC3 和 RB1 免疫组化在葡萄胎中的诊断效用。
Int J Mol Sci. 2023 Jun 2;24(11):9656. doi: 10.3390/ijms24119656.

本文引用的文献

1
Prevalence and Factors Associated with Hydatidiform Mole among Patients Undergoing Uterine Evacuation at Mbarara Regional Referral Hospital.姆巴拉拉地区转诊医院接受子宫排空术患者中葡萄胎的患病率及相关因素
Obstet Gynecol Int. 2018 Apr 1;2018:9561413. doi: 10.1155/2018/9561413. eCollection 2018.
2
Risk Factors for Hydatidiform Mole: Is Husband’s Job a Major Risk Factor?葡萄胎的危险因素:丈夫的职业是主要危险因素吗?
Asian Pac J Cancer Prev. 2017 Oct 26;18(10):2657-2662. doi: 10.22034/APJCP.2017.18.10.2657.
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Molecular genetic studies of complete hydatidiform moles.完全性葡萄胎的分子遗传学研究。
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Hyperthyroidism and pregnancy.甲状腺功能亢进与妊娠
BMJ. 2008 Mar 22;336(7645):663-7. doi: 10.1136/bmj.39462.709005.AE.
9
Diagnosis and treatment of gestational trophoblastic disease: ACOG Practice Bulletin No. 53.妊娠滋养细胞疾病的诊断与治疗:美国妇产科医师学会实践公告第53号
Gynecol Oncol. 2004 Jun;93(3):575-85. doi: 10.1016/j.ygyno.2004.05.013.
10
Thyrotropic action of human chorionic gonadotropin.人绒毛膜促性腺激素的促甲状腺作用。
Thyroid. 1995 Oct;5(5):425-34. doi: 10.1089/thy.1995.5.425.