Yin Yewei, Zhao Yang, Fu Yanyan, Xiang Aiqun, Wu Xiaoying, Wen Dan
Eye Center, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Aug 28;45(8):966-972. doi: 10.11817/j.issn.1672-7347.2020.190196.
To observe the clinical results of orthokeratology therapy in adolescents with low to moderate myopia after wearing the lens for 6 months.
The data of 69 adolescents with low to moderate myopia were retrospectively analyzed. According to the degree of spherical power before treatment, the adolescents were divided into a low myopia group (34 cases, with spherical diopter from -3.00 to -0.75 D) and a moderate myopia group (35 cases, with spherical diopter from -5.75 to -3.25 D). The changes of the uncorrected distance visual acuity (UDVA), intraocular pressure, count of endothelial cell, eye axis length, Strehl ratio (SR), modulation transfer function (MTF), Q value, and wavefront aberrations before the treatment and 6 months after the treatment were compared and analyzed between the 2 groups.
Compared with before the treatment, the UDVA improved significantly in the 2 groups (both <0.05); the intraocular pressure and the count of endothelial cell did not change obviously in the 2 groups (all >0.05), the eye axial length in the 2 groups was increased significantly (both <0.05), but there was no significant difference between the 2 groups (all >0.05); the Q value in the 2 groups was increased significantly, and the change was more obvious for the moderate myopia group (all <0.05); the SR and MTF were increased remarkably in the 2 groups (all <0.05), and there were no significant difference in the changes of SR and MTF between the 2 groups (both >0.05); a considerable decrement was found for the total aberration, the total low-order aberration, and defocus (all <0.05), and the changes were more significant in the moderate myopia group (all <0.05); the total high-order aberrations were increased in the low myopia group (<0.05); the increment of the vertical astigmatism, spherical aberration, horizontal coma, vertical coma, and horizontal trefoil were noticeable (all <0.05), and the changes of the spherical aberration, vertical coma, and horizontal trefoil were more obvious in the moderate myopia group (all <0.05).
Orthokeratology can effectively improve the visual results of the adolescents with low to moderate myopia, and the corrective effect is more obvious for the adolescents with moderate myopia than those with low myopia.
观察青少年中低度近视患者佩戴角膜塑形镜6个月后的临床效果。
回顾性分析69例青少年中低度近视患者的数据。根据治疗前球镜度数，将青少年分为低度近视组（34例，球镜度数为-3.00至-0.75D）和中度近视组（35例，球镜度数为-5.75至-3.25D）。比较分析两组治疗前及治疗6个月后裸眼远视力（UDVA）、眼压、内皮细胞计数、眼轴长度、斯特列尔比（SR）、调制传递函数（MTF）、Q值及波前像差的变化。
与治疗前相比，两组UDVA均显著提高（均P<0.05）；两组眼压及内皮细胞计数无明显变化（均P>0.05），两组眼轴长度均显著增加（均P<0.05），但两组间比较差异无统计学意义（均P>0.05）；两组Q值均显著增加，中度近视组变化更明显（均P<0.05）；两组SR和MTF均显著增加（均P<0.05），两组SR和MTF变化差异无统计学意义（均P>0.05）；总像差、总低阶像差及离焦均有显著降低（均P<0.05），中度近视组变化更显著（均P<0.05）；低度近视组总高阶像差增加（P<0.05）；垂直散光、球差、水平彗差、垂直彗差及水平三叶草像差增加明显（均P<0.05），中度近视组球差、垂直彗差及水平三叶草像差变化更明显（均P<0.05）。
角膜塑形术可有效改善青少年中低度近视的视力，对中度近视青少年的矫正效果优于低度近视青少年。
