Wang Chen, Zhang Keqiang
Department V of Gynecologic Oncology, Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Aug 28;45(8):994-998. doi: 10.11817/j.issn.1672-7347.2020.190218.
The incidence of cervical cancer ranks the first among the gynecological malignant tumors. Given the implementation of widespread cervical cancer screening and the improvement of clinical treatment, the cervical cancer mortality has decreased substantially. However, surgery, radiotherapy, and chemotherapy may impair the ovarian function, resulting in premature ovarian insufficiency and premature climacteric, which has reduced the quality of life in young patients. As a new fertility preservation technology, autologous ovarian tissue cryopreservation and transplantation is developing rapidly and showing great potentiality in preserving ovarian endocrine function of young cervical cancer patients.
宫颈癌的发病率在妇科恶性肿瘤中位居首位。鉴于广泛开展的宫颈癌筛查以及临床治疗水平的提高，宫颈癌死亡率已大幅下降。然而，手术、放疗和化疗可能会损害卵巢功能，导致卵巢早衰和过早绝经，这降低了年轻患者的生活质量。作为一种新的生育力保存技术，自体卵巢组织冷冻保存和移植发展迅速，在保留年轻宫颈癌患者卵巢内分泌功能方面显示出巨大潜力。
