Grusha Y O, Novikov M L, Danilov S S, Fettser E I, Karapetyan A S
Research Institute of Eye Diseases, Moscow, Russia.
I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Vestn Oftalmol. 2020;136(5):52-57. doi: 10.17116/oftalma202013605152.
Combined lesions of the facial and trigeminal cranial nerves are typical after neurosurgical treatment. Violation of the innervation of orbicularis muscle leads to inability to completely close the eyelids, while denervation of the cornea is often manifested as a long-term ongoing and recurring neurotrophic keratitis. The restoration of corneal innervation is a pathogenetically targeted treatment for this pathology. For this purpose, neurotrophic keratitis could be reversed via the method of corneal neurotization using contralateral . The presented clinical case demonstrates the results of the first operation of neurotization of the cornea in a patient with combined lesions of the facial and trigeminal nerves.
神经外科治疗后，面神经和三叉神经的联合损伤很典型。眼轮匝肌神经支配受损会导致无法完全闭合眼睑，而角膜去神经支配常表现为长期持续且反复发作的神经营养性角膜炎。恢复角膜神经支配是针对这种病理状况的病因靶向治疗。为此，可通过使用对侧神经的角膜神经化方法来逆转神经营养性角膜炎。本文呈现的临床病例展示了一名面神经和三叉神经联合损伤患者首次角膜神经化手术的结果。
