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机器人前列腺切除术后引入尿道周围悬吊缝线后早期控尿功能的改善。

Improvement in early continence after introduction of periurethral suspension stitch in robotic prostatectomy.

机构信息

Department of Urology, University Hospital of North Norway, 9038, Tromsø, Norway.

Department of Clinical Medicine, UiT-Arctic University of Norway, Tromsø, Norway.

出版信息

J Robot Surg. 2021 Oct;15(5):679-686. doi: 10.1007/s11701-020-01156-6. Epub 2020 Oct 14.

Abstract

Early urinary incontinence remains a major source of morbidity for patients undergoing robotic prostatectomy. The purpose of the study was to determine whether the introduction of a suspension stitch would improve early urinary continence rates in patients undergoing robotic prostatectomy for localized prostate cancer at our department. We retrospectively reviewed patients undergoing robotic prostatectomy with either suspension (n = 119) or figure-of-eight (n = 48) stitching of the dorsal venous complex. The patients submitted EPIC-26 questionnaires before surgery and after 3 and 18 months, respectively. Logistic regression analysis was run to determine the effect of the suspension stitch, nerve-sparing, posterior reconstruction, prostate volume, age and body mass index on early continence rate. The odds ratio of experiencing urinary leaks was 2.1 times higher (95% CI 1.0-4.3) in the figure-of-eight stitch group compared to the suspension stitch group 3 months after surgery (p < 0.05). The early urinary continence rate was 61.3% in the suspension stitch group compared to 35.4% in the figure-of-eight stitch group (p < 0.005). There were no differences between the groups 18 months post-prostatectomy (90.7% in the suspension stitch group versus 81.4% in the non-suspension stitch group, p = 0.1). Ordinal regression analysis identified the suspension stitch, bilateral nerve-sparing and body mass index as independent predictors of urinary continence at 3 months. The association between urinary continence and either unilateral nerve-sparing, posterior reconstruction, prostate volume or age did not reach statistical significance. Our results suggest that the suspension stitch improved early urinary continence following robotic prostatectomy.

摘要

术后早期尿失禁仍然是接受机器人前列腺切除术的患者的主要发病原因之一。本研究旨在确定在我们科接受机器人前列腺切除术治疗局限性前列腺癌的患者中,引入悬吊缝合是否会提高早期尿控率。我们回顾性分析了接受悬吊(n=119)或 8 字缝合(n=48)处理背静脉复合体的机器人前列腺切除术患者。患者分别在术前、术后 3 个月和 18 个月时提交 EPIC-26 问卷。我们采用逻辑回归分析来确定悬吊缝合、神经保留、后重建、前列腺体积、年龄和体重指数对早期尿控率的影响。与悬吊缝合组相比,3 个月后 8 字缝合组发生尿漏的可能性高 2.1 倍(95%CI 1.0-4.3)(p<0.05)。悬吊缝合组的早期尿控率为 61.3%,8 字缝合组为 35.4%(p<0.005)。前列腺切除术后 18 个月两组间无差异(悬吊缝合组为 90.7%,8 字缝合组为 81.4%,p=0.1)。有序回归分析确定了悬吊缝合、双侧神经保留和 BMI 是术后 3 个月尿控的独立预测因子。单侧神经保留、后重建、前列腺体积或年龄与尿控之间的相关性没有达到统计学意义。我们的结果表明,悬吊缝合可改善机器人前列腺切除术后的早期尿控。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5713/8423698/97eb5d2a00dc/11701_2020_1156_Fig1_HTML.jpg

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