Loayza-Gamboa Waldo, Martel-Ramirez Vladimir, Inga-Condezo Vanessa, Valderrama-Albino Vanessa, Alvarado-Villacorta Rosa, Valera-Cornejo Diego
Glaucoma Department, Instituto Nacional de Oftalmología "Francisco Contreras Campos", Lima, Perú.
Research unit, Clínica Vista, Lima, Perú.
Clin Ophthalmol. 2020 Oct 2;14:3009-3016. doi: 10.2147/OPTH.S272298. eCollection 2020.
To describe the clinical outcomes of combined prolene gonioscopy assisted transluminal trabeculotomy (GATT) with phacoemulsification in patients with open-angle glaucoma.
Retrospective study of patients with cataract and open-angle glaucoma treated with GATT and phacoemulsification with intraocular lens (IOL) implantation. Patients with neovascular glaucoma, corneal decompensation, unstable IOL, and with bleeding disorders were excluded. The cumulative probability of failure was the primary outcome. Secondary outcomes were the complete success rate, the mean change on intraocular pressure (IOP), best-corrected visual acuity (BCVA) and number of glaucoma medications at the last follow-up. The frequency of complications was also recorded.
Thirty two eyes (25 patients) were included. Nineteen (59.3%) were females, with a mean age of 73.4±12.4 (23-87 years) and a mean baseline BCVA of 1.1±0.75 (0.3-3) LogMAR units. The cumulative probability of failure was 3.2% at 1 month and 6.3% at 6 and 12 months. Sixty-eight and 65.5% of eyes achieved complete success at 3 and 6 months, respectively. The reduction of IOP and number of glaucoma medications at 6 months were statistically significant (p<0.0001 and p=0.0002, respectively). There was a statistically significant improvement of BCVA (from 1.1±0.7 to 0.4±0.7) at 6 months (p<0.0001). IOP spikes (18.7%) and transient hyphema (9.3%) were the most common complications.
Combined GATT with cataract surgery reduced the IOP and was associated with low failure rates and few ocular complications. This procedure offers the advantage to avoid the need for a bleb, scleral, or conjunctival incision, allowing the possibility for future glaucoma procedures.
描述在开角型青光眼患者中联合使用普理灵前房角镜辅助经腔小梁切开术（GATT）与超声乳化术的临床结果。
对接受GATT和超声乳化联合人工晶状体（IOL）植入治疗的白内障合并开角型青光眼患者进行回顾性研究。排除新生血管性青光眼、角膜失代偿、人工晶状体不稳定及有出血性疾病的患者。失败的累积概率是主要结局指标。次要结局指标包括完全成功率、最后一次随访时眼压（IOP）的平均变化、最佳矫正视力（BCVA）及青光眼药物使用数量。还记录了并发症的发生率。
纳入32只眼（25例患者）。其中19例（59.3%）为女性，平均年龄73.4±12.4岁（23 - 87岁），平均基线BCVA为1.1±0.75（0.3 - 3）LogMAR单位。1个月时失败的累积概率为3.2%，6个月和12个月时为6.3%。分别有68%和65.5%的眼在3个月和6个月时获得完全成功。6个月时眼压降低及青光眼药物使用数量减少具有统计学意义（分别为p<0.0001和p = 0.0002）。6个月时BCVA有统计学意义的改善（从1.1±0.7提高到0.4±0.7）（p<0.0001）。眼压峰值（18.
