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超声睫状体平坦部光凝术(GATT)治疗玻璃体视网膜手术后继发闭角型青光眼。

Gonioscopy-assisted Transluminal Trabeculotomy (GATT) in Patients With Secondary Open-Angle Glaucoma Following Vitreoretinal Surgery.

机构信息

Bascom Palmer Eye Institute, Miami, FL.

Department of Ophthalmology, University of California, Davis, Sacramento.

出版信息

J Glaucoma. 2020 Apr;29(4):e23-e25. doi: 10.1097/IJG.0000000000001461.

DOI:10.1097/IJG.0000000000001461
PMID:32053554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7467211/
Abstract

PURPOSE

To examine the short-term efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in a series of patients who developed glaucoma following vitreoretinal surgery.

PATIENTS AND METHODS

Retrospective case series of consecutive patients aged above 18 years with secondary open-angle glaucoma following vitreoretinal surgery who had undergone GATT between January 2015 and June 2019. Eyes were excluded if there is<1 month of follow-up or glaucoma before vitreoretinal surgery.

RESULTS

Eight eyes of 8 patients were included, with age range 18 to 72 years (median 43.5 y). Mean pretreatment intraocular pressure (IOP) was 32.7±5.1 mm Hg with a mean of 4.8±0.9 medications. Following GATT, mean IOP improved to 13.6±1.8 mm Hg (P<0.001) with a reduction to 1.6±1.4 medications after a mean follow-up of 8.6 months (range 1 to 25 mo). Five of the 8 eye (62.5%) had silicone oil in the vitreous cavity during GATT, none of which had concurrent oil removal.

CONCLUSIONS

GATT is a safe and effective procedure for eyes with secondary open-angle glaucoma following vitreoretinal surgery. Further studies are needed to elucidate long-term benefits of angle surgery on eyes with high pressure following vitreoretinal surgery.

摘要

目的

研究一组玻璃体视网膜手术后发生青光眼患者行房角镜辅助经巩膜隧道小梁切开术(GATT)的短期疗效和安全性。

方法

回顾性连续病例系列研究,纳入 2015 年 1 月至 2019 年 6 月期间行 GATT 的年龄大于 18 岁、继发黄斑部开角型青光眼的玻璃体视网膜手术后患者。如果随访时间<1 个月或玻璃体视网膜手术前有青光眼,则排除该眼。

结果

纳入 8 例患者的 8 只眼,年龄 18 至 72 岁(中位数 43.5 岁)。术前平均眼压(IOP)为 32.7±5.1mmHg,平均用药 4.8±0.9 种。行 GATT 后,平均 IOP 降至 13.6±1.8mmHg(P<0.001),平均随访 8.6 个月(1 至 25 个月)后降至 1.6±1.4 种药物。8 只眼中有 5 只(62.5%)玻璃体腔中有硅油,其中无一例行硅油取出术。

结论

GATT 是治疗玻璃体视网膜手术后继发黄斑部开角型青光眼的安全有效方法。需要进一步研究阐明角手术对玻璃体视网膜手术后高眼压眼的长期益处。

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Intraocular Oxygen and Antioxidant Status: New Insights on the Effect of Vitrectomy and Glaucoma Pathogenesis.眼内氧和抗氧化状态:玻璃体切割术和青光眼发病机制影响的新见解。
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