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pH对肾脏有机离子转运中性别相关差异的影响。

The influence of pH on the sex-related differences in renal organic ion transport.

作者信息

Small A, Homer L D, Ide R S

出版信息

Experientia. 1978 Oct 15;34(10):1315-6. doi: 10.1007/BF01981441.

Abstract

The stimulating effects of elevated medium pH and androgen on in vitro transport of p-aminohippurate and N-methylnicotinamide (NMN) were additive, although the androgenic effect was pH-dependent only in the case of NMN. The similarity of response of the 2 systems supports the idea of a common passive efflux pathway for organic anions and cations.

摘要

培养基pH值升高和雄激素对对氨基马尿酸和N-甲基烟酰胺(NMN)体外转运的刺激作用是相加的,尽管雄激素的作用仅在NMN的情况下依赖于pH值。这两个系统反应的相似性支持了有机阴离子和阳离子存在共同被动外排途径的观点。

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