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免疫功能正常宿主中被瓶霉属感染引起的眼眶感染

Orbital Infection by Saksenaea vasiformis in an Immunocompetent Host.

作者信息

Lumyongsatien Mingkwan, Jaru-Ampornpan Pimkwan, Uiprasertkul Mongkol, Selva Dinesh

机构信息

Department of Ophthalmology, Mettapracharak Hospital, Sampran District, 52 moo2 Rhikhing, Sampran, Nakhon Pathom, Thailand 73210.

Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Arun Amarin Road, Siriraj, Bangkoknoi, Bangkok, Thailand 10700.

出版信息

Case Rep Ophthalmol Med. 2020 Sep 30;2020:8827074. doi: 10.1155/2020/8827074. eCollection 2020.

Abstract

Orbital mucormycosis caused by is extremely rare. Herein, we report an immunocompetent 22-year-old Thai female who presented with two months of progressive right upper eyelid mass, associated with swelling, redness, and ptosis. She failed to improve despite multiple courses of antibiotic and steroid treatment. Computed tomography (CT) scan showed infiltration involving the upper eyelid and lacrimal gland. Fungal hyphae were revealed by histopathological study. Polymerase chain reaction (PCR) was positive for (GenBank: accession number FR687327.1). The patient was successfully treated with surgical debridement, amphotericin B, and oral posaconazole.

摘要

由 引起的眼眶毛霉菌病极为罕见。在此,我们报告一名免疫功能正常的22岁泰国女性,她出现进行性右上眼睑肿物两个月,伴有肿胀、发红和上睑下垂。尽管接受了多疗程的抗生素和类固醇治疗,病情仍未改善。计算机断层扫描(CT)显示上眼睑和泪腺有浸润。组织病理学研究发现了真菌菌丝。聚合酶链反应(PCR)检测 呈阳性(GenBank:登录号FR687327.1)。该患者通过手术清创、两性霉素B和口服泊沙康唑成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5401/7547347/f9b2d0d6582d/CRIOPM2020-8827074.001.jpg

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