Baldassarri L, Caprioli A, Donelli G
Microbiologica. 1987 Jul;10(3):317-23.
The penetration process of an enteroinvasive strain of Escherichia coli 0124 into HEp-2 cells has been studied by electron microscopy. Bacteria penetrated into cultured cells by a phagocytosis-like mechanism, and multiplied within the vacuoles as well as in the cytoplasmic matrix. On the whole, the infection cycle of EIEC appeared to be similar to that described for Shigella. The stain examined has also been found to elaborate a 40 nm-thick glyocalix, which is probably involved in the recognition of host surface receptors and therefore in the attachment of microorganisms to the cell membrane.
利用电子显微镜研究了肠侵袭性大肠杆菌0124菌株侵入HEp - 2细胞的过程。细菌通过类似吞噬作用的机制侵入培养细胞，并在液泡内以及细胞质基质中繁殖。总体而言，肠侵袭性大肠杆菌的感染周期似乎与志贺氏菌所描述的相似。还发现所检测的菌株能形成一层40纳米厚的糖萼，这可能参与宿主表面受体的识别，进而参与微生物与细胞膜的附着。
