Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
Scand J Urol. 2020 Dec;54(6):501-507. doi: 10.1080/21681805.2020.1832144. Epub 2020 Oct 16.
To evaluate the predictors of post-ileal conduit (IC) parastomal hernia (PSH) based on a standard grading methodology and according to the patients reported outcome measures (PROM).
A prospective evaluation for patients with IC attending their scheduled follow-up was conducted between December 2013 and October 2015. The hernia stage was determined according to the European Hernia Society (EHS) classification as types I and II included defect size 5 cm without and with a concomitant incisional hernia, respectively. Types III and IV included defect size > 5 cm without and with a concomitant incisional hernia (high-grade hernia). The evaluation was performed by a non-contrast CT scan. PROM were defined as symptomatic if there were hernia-related abdominal discomfort, appliance problems, and/or bowel complications. Perioperative parameters were modeled for prediction of high-grade and PROM outcomes.
PSH was diagnosed in 138 (39.9%) patients, symptomatic in 119 (34.4%) and high-grade in 59 (17%). Independent predictors of radiologically diagnosed PSH were hypoalbuminemia (odds ratio [OR]: 1.7; 95% Confidence interval [CI]: 1.1-2.7; = 0.02), localised disease (OR: 0.6; 95% CI: 0.3-0.9; = 0.04) and negative lymphadenopathy (OR: 0.4; 95%CI: 0.2-0.8; = 0.004). Predictors of symptomatic PSH were hypoalbuminemia (OR: 2; 95%CI: 1.2-2.3: = 0.003) and previous hernia surgery (OR: 2.1; 95%CI: 1.1-4.2; = 0.024).
Only a small proportion of patients with PSH were asymptomatic. Preoperative hypoalbuminemia was the most significant factor contributing to the development and symptomatizing of PSH. Previous hernia surgery further contributed to the patient complaint.
根据标准分级方法并根据患者报告的结果测量(PROM)评估回肠造口(IC)后旁疝(PSH)的预测因素。
对 2013 年 12 月至 2015 年 10 月期间定期接受随访的 IC 患者进行前瞻性评估。根据欧洲疝学会(EHS)分类,疝分期为 I 型和 II 型,分别为缺陷大小 <5cm 且无伴随切口疝和缺陷大小 <5cm 且伴有切口疝。III 型和 IV 型包括缺陷大小 >5cm 且无伴随切口疝(高级别疝)。评估通过非对比 CT 扫描进行。如果存在与疝相关的腹部不适、器械问题和/或肠道并发症,则将 PROM 定义为症状性。对围手术期参数进行建模,以预测高级别和 PROM 结果。
138 例(39.9%)患者诊断为 PSH,119 例(34.4%)有症状,59 例(17%)为高级别。影像学诊断 PSH 的独立预测因素为低白蛋白血症(比值比 [OR]:1.7;95%置信区间 [CI]:1.1-2.7;=0.02)、局限性疾病(OR:0.6;95%CI:0.3-0.9;=0.04)和阴性淋巴结病(OR:0.4;95%CI:0.2-0.8;=0.004)。有症状 PSH 的预测因素为低白蛋白血症(OR:2;95%CI:1.2-2.3:=0.003)和先前疝手术(OR:2.1;95%CI:1.1-4.2;=0.024)。
只有一小部分 PSH 患者无症状。术前低白蛋白血症是导致 PSH 发生和症状出现的最重要因素。先前的疝手术进一步导致患者出现抱怨。