Puylaert J B, Rutgers P H, Lalisang R I, de Vries B C, van der Werf S D, Dörr J P, Blok R A
N Engl J Med. 1987 Sep 10;317(11):666-9. doi: 10.1056/NEJM198709103171103.
The diagnosis of appendicitis is frequently difficult. We studied prospectively the diagnostic accuracy and clinical impact of abdominal ultrasonography in 111 consecutive patients thought to have appendicitis. Ultrasonography was performed with small high-resolution, linear-array transducers, with the abdomen compressed to displace or compress bowel and fat. Among 52 patients later shown in surgery to have appendicitis, ultrasonography was unequivocally positive in 39 (sensitivity, 75 percent). Of 31 patients in whom appendicitis was definitely excluded, none had a positive ultrasound examination (specificity, 100 percent). The sensitivity in those with a perforated appendix (28.5 percent) was much lower than in those with acute nonperforating appendicitis (80.5 percent) or appendiceal mass (89 percent), but the low sensitivity did not influence clinical management, since the need for surgery in patients with a perforated appendix was clinically obvious. Ultrasonography resulted in changes in the proposed management in 29 of the 111 patients (26 percent). It also led to the correct diagnosis in the 16 patients who were found to have a disease other than appendicitis. We conclude that ultrasonography is a useful aid in the diagnosis of appendicitis.
阑尾炎的诊断常常很困难。我们前瞻性地研究了腹部超声对111例连续被认为患有阑尾炎患者的诊断准确性及临床影响。超声检查使用小型高分辨率线性阵列换能器,对腹部施加压力以推移或挤压肠管和脂肪。在后来经手术证实患有阑尾炎的52例患者中,超声检查明确阳性的有39例(敏感性为75%)。在明确排除阑尾炎的31例患者中,超声检查均为阴性(特异性为100%)。阑尾穿孔患者的敏感性(28.5%)远低于急性非穿孔性阑尾炎患者(80.5%)或阑尾肿块患者(89%),但低敏感性并未影响临床处理,因为阑尾穿孔患者的手术必要性在临床上很明显。超声检查使111例患者中的29例(26%)的拟行处理发生了改变。它还对16例被发现患有阑尾炎以外疾病的患者做出了正确诊断。我们得出结论,超声检查对阑尾炎的诊断是一种有用的辅助手段。