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通过机器人技术和重量法辅助工作流程配制的静脉肿瘤输注药物的比较。

Comparison of IV oncology infusions compounded via robotics and gravimetrics-assisted workflow processes.

作者信息

Pang Bob, Earl Marc, Knoer Scott, Yaniv Angela, Willner Marc, Boyd Anthony

机构信息

Cleveland Clinic, Cleveland, OH.

American Pharmacists Association, Washington, DC.

出版信息

Am J Health Syst Pharm. 2021 Jan 5;78(2):122-134. doi: 10.1093/ajhp/zxaa366.

DOI:10.1093/ajhp/zxaa366
PMID:33064792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7665334/
Abstract

PURPOSE

A study was conducted to compare an intravenous (IV) gravimetric technology-assisted workflow (TAWF) platform to an IV robotic system. In the study we reviewed both IV technology platforms using the same gravimetric quality assurance system, which allowed for direct comparison.

METHODS

All oncology preparations compounded from January 2016 through December 2018 using either system were included in our retrospective analysis. Final preparation accuracy, IV system precision, and workflow throughput (analyzed using lean process methodologies) were evaluated.

RESULTS

Data analysis indicated that use of the IV gravimetric TAWF system was associated with a significantly lower percentage of accuracy errors compared to the IV robotics system (1.58% vs 2.47%, P < 0.001), with no significant difference in absolute precision (1.12 vs 1.12 P = 0.952). Lean analysis demonstrated that overall completion time (17:49 minutes vs 24:45 minutes) and compound preparation time (2:39 minutes vs 6:07 minutes) were less with the IV gravimetric TAWF vs the IV robotics system.

CONCLUSION

Implementation of either an IV gravimetric TAWF system or IV robotics system will result in similar compounding accuracy and precision. Preparation time was less with use of the IV gravimetric TAWF vs the IV robotic system, but the IV robotic system required less human intervention. Both systems ensure medication safety for patients, although the IV robotic system has increased safeguards in place. Therefore, the primary driver for implementing these systems is alternative factors such as cost of systems implementation and maintenance, employee safety, and drug waste.

摘要

目的

开展一项研究以比较静脉注射(IV)重量技术辅助工作流程(TAWF)平台与IV机器人系统。在该研究中,我们使用相同的重量质量保证系统对两种IV技术平台进行了评估,从而能够进行直接比较。

方法

我们的回顾性分析纳入了2016年1月至2018年12月期间使用任一系统配制的所有肿瘤制剂。评估了最终配制准确性、IV系统精度和工作流程吞吐量(使用精益流程方法进行分析)。

结果

数据分析表明,与IV机器人系统相比,使用IV重量TAWF系统的准确性误差百分比显著更低(1.58%对2.47%,P<0.001),绝对精度无显著差异(1.12对1.12,P = 0.952)。精益分析表明,与IV机器人系统相比,IV重量TAWF的总体完成时间(17:49分钟对24:45分钟)和复方制剂配制时间(2:39分钟对6:07分钟)更短。

结论

实施IV重量TAWF系统或IV机器人系统均可实现相似的配制准确性和精度。与IV机器人系统相比,使用IV重量TAWF的配制时间更短,但IV机器人系统所需的人工干预更少。两种系统均能确保患者用药安全,尽管IV机器人系统有更多保障措施。因此,实施这些系统的主要驱动因素是诸如系统实施和维护成本、员工安全以及药物浪费等其他因素。