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在白化小鼠中进行鼻硬结克雷伯菌的实验性接种。

Experimental inoculation of Klebsiella rhinoscleromatis bacilli in albino mice.

作者信息

Toppozada H, Gaafar H

出版信息

ORL J Otorhinolaryngol Relat Spec. 1987;49(4):214-7. doi: 10.1159/000275938.

Abstract

72 albino mice were intranasally inoculated with Klebsiella rhinoscleromatis suspension with or without the addition of hog mucin. Scleroma-like lesions developed in their lungs more frequently with hog mucin. A liver affection was detected only in 1 animal. K. rhinoscleromatis organisms were recovered from the lung lesions. A possible potentiating effect of hog mucin is discussed.

摘要

72只白化小鼠经鼻接种了添加或未添加猪粘蛋白的鼻硬结克雷伯菌悬液。添加猪粘蛋白后,它们肺部出现硬皮瘤样病变的频率更高。仅在1只动物中检测到肝脏病变。从肺部病变中分离出了鼻硬结克雷伯菌。讨论了猪粘蛋白可能的增强作用。

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