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心理社会干预对减少酒精问题患者自杀行为及饮酒量的影响:随机对照试验的系统评价

Psychosocial Interventions for Reducing Suicidal Behaviour and Alcohol Consumption in Patients With Alcohol Problems: A Systematic Review of Randomized Controlled Trials.

作者信息

Hurzeler Tristan, Giannopoulos Vicki, Uribe Gabriela, Louie Eva, Haber Paul, Morley Kirsten C

机构信息

Discipline of Addiction Medicine, Central Clinical School, Faculty of Medicine and Health, The University of Sydney, NSW, Australia.

Drug Health Services, Royal Prince Alfred Hospital, NSW, Australia.

出版信息

Alcohol Alcohol. 2021 Jan 4;56(1):17-27. doi: 10.1093/alcalc/agaa094.

Abstract

OBJECTIVE

We aimed to provide a synthesis and evaluation of psychosocial interventions to prevent suicide and reduce self-harm, as well as alcohol intake, for patients with alcohol problems.

METHODS

The systematic review was carried out according to the PRISMA guidelines and considered articles published in English from all countries. Terms relating to suicidality and alcohol problems were used to search Medline, EMBASE and PsycINFO databases. Randomized controlled trials of psychosocial interventions targeted for outpatient settings were included.

RESULTS

Six studies with a total of 400 participants were included. Two investigated dialectic behavioural therapy (DBT), one internet-delivered DBT, one dynamic deconstructivist psychotherapy (DDP) and two integrated cognitive behavioural therapy (CBT). Face to face and online DBT was significantly associated with abstinence and reductions in consumption with only a trend for a reduction in suicide attempts in one study relative to treatment at usual (TAU). DDP yielded significant reductions in alcohol consumption and suicide attempts versus community care. CBT was significantly effective relative to TAU in reducing alcohol use and suicide attempts in one trial with adolescents but not in another trial in an adult population.

CONCLUSION

Integrated CBT has promise for adolescents, DBT may be helpful for alcohol patients with borderline personality disorder and iDBT may be useful for the wider community with heavy alcohol use. However, given the paucity of studies and the exploratory nature of these trials, there is currently no strong evidence for an effective psychosocial intervention to reduce alcohol consumption and suicidal behaviour in adults with problematic alcohol use.

摘要

目的

我们旨在对心理社会干预措施进行综合分析和评估,以预防酒精问题患者自杀、减少其自我伤害行为以及酒精摄入量。

方法

根据PRISMA指南进行系统评价,并纳入所有国家以英文发表的文章。使用与自杀倾向和酒精问题相关的术语检索Medline、EMBASE和PsycINFO数据库。纳入针对门诊环境的心理社会干预随机对照试验。

结果

共纳入6项研究,总计400名参与者。两项研究调查了辩证行为疗法(DBT),一项为互联网提供的DBT,一项为动态解构主义心理治疗(DDP),两项为综合认知行为疗法(CBT)。面对面和在线DBT与戒酒及饮酒量减少显著相关,在一项研究中,相对于常规治疗(TAU),仅存在自杀未遂减少的趋势。与社区护理相比,DDP在减少酒精消费和自杀未遂方面有显著效果。在一项针对青少年的试验中,CBT相对于TAU在减少酒精使用和自杀未遂方面显著有效,但在另一项针对成年人群的试验中则不然。

结论

综合CBT对青少年有前景,DBT可能对边缘型人格障碍的酒精患者有帮助,而互联网提供的DBT(iDBT)可能对大量饮酒的更广泛社区有用。然而,鉴于研究数量较少且这些试验具有探索性,目前尚无有力证据表明存在有效的心理社会干预措施可减少有酒精使用问题的成年人的酒精消费和自杀行为。

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