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慢性疼痛与双相情感障碍退伍军人情绪症状之间的关系。

Relationships between chronic pain and mood symptoms among veterans with bipolar disorder.

机构信息

VA Capital Healthcare Network Mental Illness, Research, Education, and Clinical Center (MIRECC), Baltimore, MD 21201, United States.

VA Capital Healthcare Network Mental Illness, Research, Education, and Clinical Center (MIRECC), Baltimore, MD 21201, United States.

出版信息

J Affect Disord. 2020 Dec 1;277:765-771. doi: 10.1016/j.jad.2020.08.069. Epub 2020 Sep 1.

DOI:10.1016/j.jad.2020.08.069
PMID:33065815
Abstract

BACKGROUND

Chronic pain is highly prevalent among individuals with mood disorders. While much is known about the relationship between pain and unipolar depression, little is known about pain experiences among people with bipolar disorder. This pilot study addresses this gap by examining pain and its relationship to mood and functioning in a sample of US military veterans with bipolar disorder.

METHODS

Qualitative interviews were conducted with 15 veterans with bipolar disorder and chronic pain who were recruited from outpatient services within a Veterans Affairs medical center.

RESULTS

Veterans reported a bidirectional relationship between pain and bipolar depression. When discussing manic episodes, individuals' experiences varied between notable reductions in pain (usually in euphoric states), increases in pain (usually in angry/irritable states), and feeling disconnected from pain. Many reported that increased activity when manic contributed to worse pain after an episode. Veterans clearly articulated how these connections negatively affected their functioning and quality of life.

LIMITATIONS

This was a small, retrospective study that included a non-random sample of veteran participants from one VA medical center. All veterans were engaged in outpatient mental health care, so the majority reported that their mood has been well-stabilized through medications and/or psychotherapy.

CONCLUSIONS

Chronic pain experiences appear to be related to depressive and manic mood states and significantly affects functioning and quality of life in Veterans with bipolar disorder. This study highlights the need to assess chronic pain among veterans with bipolar disorder, as changes in mood could have significant implications for functioning and pain management.

摘要

背景

慢性疼痛在情绪障碍患者中普遍存在。虽然人们对疼痛与单相抑郁之间的关系了解很多,但对双相情感障碍患者的疼痛体验知之甚少。这项初步研究通过检查美国退伍军人双相情感障碍和慢性疼痛患者样本中的疼痛及其与情绪和功能的关系,弥补了这一空白。

方法

对 15 名患有双相情感障碍和慢性疼痛的退伍军人进行了定性访谈,这些退伍军人是从退伍军人事务部医疗中心的门诊服务中招募的。

结果

退伍军人报告疼痛与双相抑郁之间存在双向关系。在讨论躁狂发作时,个体的经历在疼痛明显减轻(通常在欣快状态下)、疼痛增加(通常在愤怒/易怒状态下)和感觉与疼痛脱节之间有所不同。许多人报告说,躁狂时活动增加会导致发作后疼痛加剧。退伍军人清楚地阐明了这些联系如何对他们的功能和生活质量产生负面影响。

局限性

这是一项小型回顾性研究,包括来自一家退伍军人事务部医疗中心的非随机退伍军人参与者样本。所有退伍军人都接受门诊心理健康护理,因此大多数人报告说,他们的情绪已经通过药物和/或心理疗法得到很好的稳定。

结论

慢性疼痛经历似乎与抑郁和躁狂情绪状态有关,并严重影响双相情感障碍退伍军人的功能和生活质量。这项研究强调了在双相情感障碍退伍军人中评估慢性疼痛的必要性,因为情绪变化可能对功能和疼痛管理产生重大影响。

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