Humanitas University, Department of Biomedical Sciences, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Milan, Italy; Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, Via Roma 16, 22032 Albese con Cassano, Como, Italy.
Humanitas University, Department of Biomedical Sciences, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Milan, Italy; Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, Via Roma 16, 22032 Albese con Cassano, Como, Italy.
J Affect Disord. 2020 Dec 1;277:772-778. doi: 10.1016/j.jad.2020.09.015. Epub 2020 Sep 7.
The wearing of respiratory protective devices (RPDs) correctly and continually in situations where people are at risk of respiratory infections is crucial for infection prevention. Certain people are poorly compliant with RPDs due to RPD-related annoyance, including respiratory discomfort. We hypothesized that individuals vulnerable to panic attacks are included in this group. No published studies on this topic are available. The evidence for our hypothesis was reviewed in this study as a starting point for future research.
We selected a set of experimental studies that measured the respiratory physiological burden in RPD wearers through objective and validated methods. We conducted a bibliographic search of publications in the PubMed database (January 2000-May 2020) to identify representative studies that may be of interest for panic respiratory pathophysiology.
Five studies were included. Wearing RPDs exerted significant respiratory effects, including increased breathing resistance, CO rebreathing due to CO accumulation in the RPD cavity, and decreased inhaled O concentration. We discussed the implications of these effects on the respiratory pathophysiology of panic.
Most studies had a small sample size, with a preponderance of young participants. Different methodologies were used across the studies. Furthermore, differences in physical responses between wearing RPDs in experimental settings or daily life cannot be excluded.
This research supports the idea that panic-prone individuals may be at higher risk of respiratory discomfort when wearing RPDs, thereby reducing their tolerance for these devices. Strategies to decrease discomfort should be identified to overcome the risk of poor compliance.
在人们有感染呼吸道传染病风险的情况下，正确且持续地佩戴呼吸防护设备（RPD）对于感染预防至关重要。由于与 RPD 相关的不适，包括呼吸不适，某些人对 RPD 的依从性较差。我们假设易患惊恐发作的人属于这一群体。目前尚无关于此主题的已发表研究。本研究回顾了我们假设的证据，作为未来研究的起点。
我们选择了一组通过客观和验证方法测量 RPD 佩戴者呼吸生理负担的实验研究。我们在 PubMed 数据库（2000 年 1 月至 2020 年 5 月）中进行了文献检索，以确定可能对惊恐呼吸病理生理学感兴趣的代表性研究。
共纳入 5 项研究。佩戴 RPD 会产生显著的呼吸影响，包括呼吸阻力增加、由于 CO 在 RPD 腔中积聚而导致 CO 再呼吸以及吸入 O 浓度降低。我们讨论了这些影响对惊恐呼吸病理生理学的意义。
大多数研究样本量较小，参与者主要为年轻人。研究中使用了不同的方法。此外，不能排除在实验环境或日常生活中佩戴 RPD 时身体反应的差异。
这项研究支持这样一种观点，即易惊恐发作的个体在佩戴 RPD 时可能更容易出现呼吸不适，从而降低他们对这些设备的耐受性。应确定减少不适的策略，以克服依从性差的风险。
